Hs03569673_cn

• Gene Symbol: RGS14
• Assay Reference Genome Location: Chr.5:177361246 on build GRCh38
• Cytoband: 5q35.3

Target Gene Details

• Entrez Gene ID: 10636
• Gene Name: regulator of G-protein signaling 14
• Gene Aliases: -
• Location: Chr.5:177357671-177372601 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RGS14	NM_006480.4			NP_006471.2
	XM_005265794.4			XP_005265851.1
	XM_005265795.4			XP_005265852.1
	AK123382.1			BAC85600.1
	BC014094.2			AAH14094.1
	BI752372.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471057	Chr.5:177310308 - 177469411 on Build GRCh38	Loss	SLC34A1 MXD3 PRR7 GRK6 PRR7-AS1 LMAN2 F12 DBN1 PFN3 RGS14
nsv509103	Chr.5:177308751 - 177414575 on Build GRCh38	Insertion	SLC34A1 MXD3 LMAN2 F12 PFN3 RGS14
nsv600364	Chr.5:177299634 - 177432847 on Build GRCh38	Loss	SLC34A1 MXD3 GRK6 LMAN2 F12 RAB24 PRELID1 NSD1 PFN3 RGS14
dgv10184n54	Chr.5:177357511 - 177469411 on Build GRCh38	Loss	SLC34A1 PRR7 GRK6 PRR7-AS1 F12 DBN1 PFN3 RGS14
nsv1161313	Chr.5:177356552 - 177463415 on Build GRCh38	Duplication	SLC34A1 PRR7 GRK6 PRR7-AS1 F12 DBN1 PFN3 RGS14
nsv428132	Chr.5:177191316 - 177375443 on Build GRCh38	Gain	MXD3 LMAN2 RAB24 PRELID1 NSD1 RGS14
nsv1161312	Chr.5:177322159 - 177405557 on Build GRCh38	Deletion	SLC34A1 LMAN2 F12 PFN3 RGS14
nsv1161311	Chr.5:177305104 - 177546474 on Build GRCh38	Duplication	PRR7-AS1 LMAN2 PRELID1 DBN1 PDLIM7 PFN3 DOK3 FAM193B SLC34A1 MXD3 PRR7 GRK6 F12 DDX41 RGS14

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleocytoplasmic transport
response to oxidative stress
spindle organization
chromosome segregation
mitotic nuclear division
learning
long-term memory
regulation of G-protein coupled receptor protein signaling pathway
visual learning
zygote asymmetric cell division
negative regulation of synaptic plasticity
intracellular signal transduction
negative regulation of MAP kinase activity
positive regulation of GTPase activity
regulation of DNA-templated transcription in response to stress
platelet-derived growth factor receptor signaling pathway
positive regulation of neurogenesis
cell division
long-term synaptic potentiation
negative regulation of ERK1 and ERK2 cascade

Function(s)

G-protein alpha-subunit binding
receptor signaling protein activity
GDP-dissociation inhibitor activity
GTPase activator activity
protein binding
microtubule binding
protein kinase binding
receptor signaling complex scaffold activity
GTPase activating protein binding