Hs03616775_cn

• Gene Symbol: GLO1
• Assay Reference Genome Location: Chr.6:38689481 on build GRCh38
• Cytoband: 6p21.2

Target Gene Details

• Entrez Gene ID: 2739
• Gene Name: glyoxalase I
• Gene Aliases: GLOD1, GLYI, HEL-S-74
• Location: Chr.6:38675925-38703176 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLO1	NM_006708.2			NP_006699.2
	AB209801.1			BAD93038.1
	AK129573.1
	AK130312.1
	AK293345.1
	AK312662.1
	AL833442.1
	BC001741.1			AAH01741.1
	BC011365.1			AAH11365.1
	BC015934.1			AAH15934.1
	BT019987.1			AAV38790.1
	BT019988.1			AAV38791.1
	D13315.1			BAA02572.1
	DA342581.1
	FJ224325.1
	KJ534846.1
	L07837.1			AAA52565.1
	S83285.1			AAB49495.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830642	Chr.6:38677280 - 38832881 on Build GRCh38	Loss	GLO1 DNAH8
nsv428144	Chr.6:38621193 - 38743309 on Build GRCh38	Gain	GLO1 BTBD9 DNAH8
nsv1015689	Chr.6:36550916 - 39052434 on Build GRCh38	Gain	CMTR1 MIR4462 CCDC167 MTCH1 MIR3925 GLO1 BTBD9 TBC1D22B SRSF3 RAB44 PPIL1 LOC107986531 LOC100505530 CPNE5 CDKN1A FGD2 C6orf89 RNF8 ZFAND3 PANDAR PI16 LOC100131047 TMEM217 MDGA1 GLP1R PIM1 DNAH8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase

Gene Ontology Categories:

Process(es)

carbohydrate metabolic process
pyruvate metabolic process
regulation of transcription from RNA polymerase II promoter
glutathione metabolic process
methylglyoxal metabolic process
osteoclast differentiation
negative regulation of apoptotic process

Function(s)

lactoylglutathione lyase activity
zinc ion binding