Hs03637161_cn

• Gene Symbol: AHR
• Assay Reference Genome Location: Chr.7:17316852 on build GRCh38
• Cytoband: 7p21.1

Target Gene Details

• Entrez Gene ID: 196
• Gene Name: aryl hydrocarbon receptor
• Gene Aliases: bHLHe76
• Location: Chr.7:17298652-17346151 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AHR	NM_001621.4			NP_001612.1
	AK307495.1
	BC069390.1			AAH69390.1
	BC070080.1			AAH70080.1
	D16354.1			BAA03857.1
	L19872.1			AAA16210.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3891076	Chr.7:16794737 - 17707004 on Build GRCh38	Gain	AHR AGR3 AGR2 KCCAT333 LOC101927630 LOC105375172
esv34717	Chr.7:17092311 - 17391136 on Build GRCh38	Gain	AHR KCCAT333
nsv8064	Chr.7:17073321 - 17404419 on Build GRCh38	Gain	AHR KCCAT333
nsv1029065	Chr.7:17131443 - 17325465 on Build GRCh38	Loss	AHR
dgv6290n100	Chr.7:16874165 - 17376469 on Build GRCh38	Gain	AHR AGR3 KCCAT333
esv3612420	Chr.7:17207915 - 17381302 on Build GRCh38	Loss	AHR KCCAT333
dgv6289n100	Chr.7:16230707 - 17452994 on Build GRCh38	Gain	TSPAN13 ISPD BZW2 AHR SOSTDC1 ANKMY2 ISPD-AS1 AGR3 AGR2 KCCAT333 LOC105375172 LRRC72
esv2422294	Chr.7:17201331 - 17452219 on Build GRCh38	Duplication	AHR KCCAT333 LOC105375172
esv3891077	Chr.7:17172449 - 17590374 on Build GRCh38	Gain	AHR KCCAT333 LOC101927630 LOC105375172
esv2759515	Chr.7:16970429 - 17491855 on Build GRCh38	Gain+Loss	AHR KCCAT333 LOC101927630 LOC105375172
esv2764001	Chr.7:17009186 - 17370140 on Build GRCh38	Gain+Loss	AHR
nsv464399	Chr.7:17046315 - 17715960 on Build GRCh38	Gain	AHR KCCAT333 LOC101927630 LOC105375172
nsv464398	Chr.7:16875904 - 17375160 on Build GRCh38	Gain	AHR AGR3 KCCAT333
dgv11225n54	Chr.7:16868921 - 17375160 on Build GRCh38	Gain	AHR AGR3 KCCAT333

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

ovarian follicle development
blood vessel development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
xenobiotic metabolic process
apoptotic process
cell cycle
response to xenobiotic stimulus
response to toxic substance
regulation of gene expression
intracellular receptor signaling pathway
regulation of B cell proliferation
response to estradiol
circadian regulation of gene expression
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cellular response to glucocorticoid stimulus

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
aryl hydrocarbon receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
enhancer binding
transcription regulatory region DNA binding
protein heterodimerization activity
protein dimerization activity
Hsp90 protein binding
E-box binding