Hs03657797_cn

• Gene Symbol: GPT
• Assay Reference Genome Location: Chr.8:144502783 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2875
• Gene Name: glutamic--pyruvic transaminase
• Gene Aliases: AAT1, ALT1, GPT1
• Location: Chr.8:144502217-144507174 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GPT	XM_011516993.2	1	567	XP_011515295.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	PLEC SCRT1 GPT PARP10 CYHR1 SMPD5 RECQL4 MIR6849 MIR6893 MIR1234 MIR939 ADCK5 EXOSC4 LOC101928953 MIR661 VPS28 MROH1 KIFC2 WDR97 TONSL GPAA1 MIR6847 MIR6846 HGH1 MAF1 MIR6848 SHARPIN FOXH1 PPP1R16A SPATC1 OPLAH DGAT1 HSF1 MIR7112 CYC1 SCX SLC52A2 TONSL-AS1 TMEM249 CPSF1 FBXL6 MFSD3 LOC101928902 SLC39A4 LRRC14 BOP1 GRINA
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	LOC101928953 LRRC24 PPP1R16A GPT C8orf82 RECQL4 MFSD3 ARHGAP39 LRRC14
esv3619130	Chr.8:144500159 - 144504908 on Build GRCh38	Gain	LOC101928953 PPP1R16A GPT
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	GPT CYHR1 RECQL4 MIR6849 MIR6893 MIR1234 MIR939 ADCK5 LOC101928953 VPS28 KIFC2 TONSL FOXH1 PPP1R16A C8orf82 SLC52A2 LRRC24 TONSL-AS1 TMEM249 CPSF1 FBXL6 MFSD3 ARHGAP39 LOC101928902 SLC39A4 LRRC14
dgv1207n67	Chr.8:144498396 - 144532417 on Build GRCh38	Gain	LOC101928953 LRRC24 PPP1R16A GPT C8orf82 RECQL4 MFSD3 ARHGAP39 LRRC14
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	LOC101928953 LRRC24 FOXH1 PPP1R16A TONSL-AS1 GPT CYHR1 KIFC2 RECQL4 MFSD3 LRRC14 TONSL
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	FOXH1 PPP1R16A GPT CYHR1 RECQL4 MIR6893 LOC101928953 LRRC24 VPS28 TONSL-AS1 KIFC2 MFSD3 SLC39A4 LRRC14 TONSL
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	LOC101928953 PPP1R16A GPT RECQL4 MFSD3
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	SCRT1 GPT CYHR1 RECQL4 MIR6849 MIR6893 MIR1234 MIR939 ADCK5 LOC101928953 VPS28 KIFC2 TONSL MIR6848 FOXH1 PPP1R16A DGAT1 HSF1 SLC52A2 TONSL-AS1 TMEM249 CPSF1 FBXL6 MFSD3 LOC101928902 SLC39A4 BOP1
dgv12443n54	Chr.8:144502322 - 144518490 on Build GRCh38	Loss	LOC101928953 GPT RECQL4 MFSD3 LRRC14
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	PLEC SCRT1 GPT PARP10 CYHR1 SMPD5 RECQL4 MIR6849 MIR6893 MIR1234 MIR939 ADCK5 EXOSC4 LOC101928953 MIR661 VPS28 MROH1 KIFC2 WDR97 TONSL GPAA1 MIR6847 MIR6846 HGH1 MAF1 MIR6848 SHARPIN FOXH1 PPP1R16A SPATC1 OPLAH DGAT1 HSF1 MIR7112 CYC1 SCX SLC52A2 TONSL-AS1 TMEM249 CPSF1 FBXL6 MFSD3 LOC101928902 SLC39A4 LRRC14 BOP1 GRINA
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	FOXH1 PPP1R16A GPT CYHR1 C8orf82 RECQL4 LOC101928953 LRRC24 TONSL-AS1 KIFC2 MFSD3 ARHGAP39 LRRC14 TONSL
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	SCRT1 GPT CYHR1 SMPD5 RECQL4 MIR6849 MIR6893 MIR1234 MIR939 ADCK5 EXOSC4 LOC101928953 VPS28 MROH1 KIFC2 WDR97 TONSL GPAA1 MIR6847 MIR6846 HGH1 MAF1 MIR6848 SHARPIN FOXH1 PPP1R16A C8orf82 SPATC1 OPLAH DGAT1 HSF1 MIR7112 CYC1 SCX ZNF251 SLC52A2 LRRC24 TONSL-AS1 TMEM249 CPSF1 FBXL6 MFSD3 ARHGAP39 LOC101928902 SLC39A4 LRRC14 BOP1
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	LOC101928953 LRRC24 FOXH1 PPP1R16A GPT CYHR1 KIFC2 RECQL4 MFSD3 LRRC14

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transaminase

Gene Ontology Categories:

Process(es)

cellular amino acid biosynthetic process
L-alanine catabolic process

Function(s)

L-alanine:2-oxoglutarate aminotransferase activity
pyridoxal phosphate binding