Hs03659892_cn

• Gene Symbol: SGK223
• Assay Reference Genome Location: Chr.8:8348722 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 157285
• Gene Name: homolog of rat pragma of Rnd2
• Gene Aliases: PRAGMIN
• Location: Chr.8:8317731-8386444 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SGK223	NM_001080826.2			NP_001074295.2
	XM_005272369.4			XP_005272426.2
	XM_005272370.4			XP_005272427.2
	XM_011543813.2			XP_011542115.1
	AK122582.1			BAC56923.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv610154	Chr.8:8244119 - 8470591 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2764098	Chr.8:7102311 - 8743201 on Build GRCh38	Gain+Loss	DEFB104B PRR23D1 DEFB103A USP17L3 USP17L1 SGK223 DEFB106A FAM90A10P LOC107986910 MIR548I3 LOC101928095 DEFB4B DEFB104A PRR23D2 OR7E154P FAM90A7P LINC00965 DEFB4A DEFB107A SPAG11B DEFB103B ZNF705B DEFB105B DEFB109P1B DEFB107B USP17L8 ZNF705G CLDN23 LOC101929400 OR7E125P DEFB105A FAM66E SPAG11A FAM66B DEFB108P1 USP17L4 DEFB106B FAM86B3P
nsv610153	Chr.8:8240557 - 8597021 on Build GRCh38	Loss	SGK223 FAM86B3P
nsv831227	Chr.8:8347322 - 8509650 on Build GRCh38	Gain+Loss	SGK223
esv2759589	Chr.8:6874198 - 8449233 on Build GRCh38	Gain+Loss	PRR23D1 DEFA10P DEFA9P DEFT1P USP17L3 DEFA3 USP17L1 FAM90A10P LOC107986910 DEFA8P FAM90A7P LINC00965 DEFB4A SPAG11B DEFB103B ZNF705B DEFB105B DEFB109P1B USP17L8 DEFB105A DEFT1P2 DEFB108P1 DEFB104B DEFB103A DEFB1 DEFA6 SGK223 DEFB106A MIR548I3 LOC101928095 DEFB4B DEFB104A DEFA1 PRR23D2 OR7E154P DEFB107A DEFA7P DEFB107B DEFA5 ZNF705G DEFA11P LOC101929400 OR7E125P DEFA1B FAM66E SPAG11A FAM66B DEFA4 USP17L4 DEFB106B FAM86B3P
nsv610156	Chr.8:8305721 - 8349823 on Build GRCh38	Loss	SGK223

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine phosphorylation

Function(s)

protein kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding