Hs03670134_cn

• Gene Symbol: SGK223
• Assay Reference Genome Location: Chr.8:8318991 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 157285
• Gene Name: homolog of rat pragma of Rnd2
• Gene Aliases: PRAGMIN
• Location: Chr.8:8317731-8386444 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SGK223	NM_001080826.2	5	3471	NP_001074295.2
	XM_005272369.4	6	3594	XP_005272426.2
	XM_005272370.4	6	4059	XP_005272427.2
	AK122582.1	5	3316	BAC56923.1
	AL833872.1	2	928	CAD38729.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv610154	Chr.8:8244119 - 8470591 on Build GRCh38	Loss	FAM86B3P SGK223
esv2764098	Chr.8:7102311 - 8743201 on Build GRCh38	Gain+Loss	DEFB106B DEFB4B MIR548I3 DEFB106A DEFB105A DEFB103B FAM66B OR7E125P FAM66E FAM86B3P SPAG11B PRR23D1 CLDN23 USP17L1 DEFB108P1 LOC101928095 PRR23D2 USP17L4 DEFB105B DEFB4A LOC107986910 USP17L8 LOC101929400 LINC00965 ZNF705B SGK223 DEFB107A DEFB104B DEFB104A FAM90A10P OR7E154P SPAG11A DEFB103A USP17L3 FAM90A7P ZNF705G DEFB109P1B DEFB107B
nsv610153	Chr.8:8240557 - 8597021 on Build GRCh38	Loss	FAM86B3P SGK223
esv2759589	Chr.8:6874198 - 8449233 on Build GRCh38	Gain+Loss	DEFB106A DEFT1P2 DEFB105A DEFA10P DEFB1 FAM66B USP17L1 DEFB108P1 PRR23D2 DEFB105B DEFB4A DEFA1 LOC101929400 DEFB107A DEFB104B DEFB104A DEFA9P DEFA7P FAM90A10P DEFB103A ZNF705G DEFB107B DEFB106B DEFB4B DEFT1P MIR548I3 DEFA1B DEFB103B DEFA11P OR7E125P FAM66E FAM86B3P SPAG11B PRR23D1 LOC101928095 USP17L4 DEFA3 LOC107986910 USP17L8 DEFA8P LINC00965 ZNF705B SGK223 OR7E154P DEFA4 SPAG11A DEFA5 USP17L3 DEFA6 FAM90A7P DEFB109P1B
nsv610156	Chr.8:8305721 - 8349823 on Build GRCh38	Loss	SGK223

More Information

Additional Information:

For this assay, SNP(s) [rs116402506] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine phosphorylation

Function(s)

protein kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding