Hs03677053_cn

• Gene Symbol: TGS1
• Assay Reference Genome Location: Chr.8:55791902 on build GRCh38
• Cytoband: 8q12.1

Target Gene Details

• Entrez Gene ID: 96764
• Gene Name: trimethylguanosine synthase 1
• Gene Aliases: NCOA6IP, PIMT, PIPMT
• Location: Chr.8:55773232-55826445 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TGS1	NM_001317902.1			NP_001304831.1
	NM_024831.7			NP_079107.6
	XM_005251328.2			XP_005251385.1
	XM_006716485.2			XP_006716548.1
	XM_017014004.1			XP_016869493.1
	AF286340.1			AAK83025.1
	AF432215.1			AAL99922.1
	AK055178.1
	AK314693.1
	AY028423.1			AAK27730.1
	AY534911.1			AAT02709.1
	BX648548.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv459n21	Chr.8:55676869 - 56030580 on Build GRCh38	Gain	LYN TMEM68 TGS1
nsv527341	Chr.8:55679732 - 55895699 on Build GRCh38	Gain	LYN TMEM68 TGS1
nsv611393	Chr.8:55763923 - 55993509 on Build GRCh38	Gain	LYN TMEM68 TGS1
esv2422388	Chr.8:55707094 - 55812437 on Build GRCh38	Duplication	TMEM68 TGS1
nsv611392	Chr.8:55741553 - 55878302 on Build GRCh38	Gain	LYN TMEM68 TGS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

spliceosomal snRNP assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
7-methylguanosine RNA capping
ribonucleoprotein complex biogenesis
7-methylguanosine cap hypermethylation
cellular lipid metabolic process
ribonucleoprotein complex import into nucleus

Function(s)

protein binding
RNA methyltransferase activity
RNA trimethylguanosine synthase activity