Hs03678132_cn

• Gene Symbol: FGF17
• Assay Reference Genome Location: Chr.8:22044236 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 8822
• Gene Name: fibroblast growth factor 17
• Gene Aliases: FGF-13, FGF-17, HH20
• Location: Chr.8:22039708-22048809 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FGF17	NM_001304478.1			NP_001291407.1
	NM_003867.3			NP_003858.1
	XM_011544683.1			XP_011542985.1
	XM_011544684.2			XP_011542986.1
	XM_011544685.1			XP_011542987.1
	AB009249.1			BAA25429.1
	AY358869.1			AAQ89228.1
	BC069475.1			AAH69475.1
	BC105131.1			AAI05132.1
	BC113489.1
	BC143789.1
	DR159037.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528590	Chr.8:22034428 - 22168131 on Build GRCh38	Loss	LGI3 SFTPC NPM2 FGF17 BMP1 FAM160B2 REEP4 DMTN NUDT18 HR
nsv610764	Chr.8:22031342 - 22094715 on Build GRCh38	Loss	NPM2 FGF17 FAM160B2 DMTN
nsv610765	Chr.8:22043573 - 22149780 on Build GRCh38	Loss	LGI3 FGF17 FAM160B2 REEP4 DMTN NUDT18 HR
nsv951112	Chr.8:22023690 - 22135287 on Build GRCh38	Deletion	NPM2 FGF17 FAM160B2 DMTN NUDT18 HR
nsv831263	Chr.8:22031088 - 22184413 on Build GRCh38	Loss	LGI3 SFTPC NPM2 FGF17 BMP1 FAM160B2 REEP4 DMTN NUDT18 HR
esv2759604	Chr.8:20675533 - 23254096 on Build GRCh38	Loss	PEBP4 NPM2 LOC101929237 PIWIL2 GFRA2 DMTN LOC107984124 DOK2 TNFRSF10B LGI3 PPP3CC LOC102467222 TNFRSF10A XPO7 EGR3 BMP1 SLC39A14 CHMP7 CCAR2 NUDT18 HR POLR3D LOC389641 RHOBTB2 BIN3 SORBS3 LOC254896 FGF17 MIR320A LOC101929172 TNFRSF10D C8orf58 SFTPC PDLIM2 TNFRSF10C PHYHIP LOC107986876 LOC100507071 BIN3-IT1 LOC286114 FAM160B2 REEP4 LOC286059

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
signal transduction
cell-cell signaling
nervous system development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
type 1 fibroblast growth factor receptor binding
type 2 fibroblast growth factor receptor binding
growth factor activity
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity