Hs03685050_cn

• Gene Symbol: FGF17
• Assay Reference Genome Location: Chr.8:22045138 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 8822
• Gene Name: fibroblast growth factor 17
• Gene Aliases: FGF-13, FGF-17, HH20
• Location: Chr.8:22039708-22048809 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FGF17	NM_001304478.1			NP_001291407.1
	NM_003867.3			NP_003858.1
	XM_005273675.1	1	467	XP_005273732.1
	XM_011544683.1			XP_011542985.1
	XM_011544684.2			XP_011542986.1
	XM_011544685.1			XP_011542987.1
	AB009249.1			BAA25429.1
	AK091643.1	1	467
	AY358869.1			AAQ89228.1
	BC069475.1			AAH69475.1
	BC105131.1			AAI05132.1
	BC113489.1
	BC143789.1
	DR159037.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528590	Chr.8:22034428 - 22168131 on Build GRCh38	Loss	DMTN FAM160B2 NPM2 SFTPC REEP4 FGF17 NUDT18 BMP1 HR LGI3
nsv610764	Chr.8:22031342 - 22094715 on Build GRCh38	Loss	DMTN FAM160B2 NPM2 FGF17
nsv610765	Chr.8:22043573 - 22149780 on Build GRCh38	Loss	DMTN FAM160B2 REEP4 FGF17 NUDT18 HR LGI3
nsv951112	Chr.8:22023690 - 22135287 on Build GRCh38	Deletion	DMTN FAM160B2 NPM2 FGF17 NUDT18 HR
nsv831263	Chr.8:22031088 - 22184413 on Build GRCh38	Loss	DMTN FAM160B2 NPM2 SFTPC REEP4 FGF17 NUDT18 BMP1 HR LGI3
esv2759604	Chr.8:20675533 - 23254096 on Build GRCh38	Loss	LOC100507071 DOK2 LOC102467222 RHOBTB2 LOC107986876 NPM2 TNFRSF10B LOC286059 EGR3 LOC389641 FAM160B2 LOC107984124 TNFRSF10C TNFRSF10A XPO7 LGI3 LOC286114 DMTN C8orf58 SORBS3 LOC101929172 PDLIM2 PHYHIP TNFRSF10D NUDT18 CHMP7 HR LOC101929237 CCAR2 PPP3CC GFRA2 MIR320A BIN3-IT1 SLC39A14 SFTPC REEP4 FGF17 PEBP4 LOC254896 BMP1 PIWIL2 BIN3 POLR3D

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
signal transduction
cell-cell signaling
nervous system development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
type 1 fibroblast growth factor receptor binding
type 2 fibroblast growth factor receptor binding
growth factor activity
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity