Hs03697170_cn

• Gene Symbol: SGK223
• Assay Reference Genome Location: Chr.8:8327184 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 157285
• Gene Name: homolog of rat pragma of Rnd2
• Gene Aliases: PRAGMIN
• Location: Chr.8:8317731-8386444 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SGK223	NM_001080826.2			NP_001074295.2
	XM_005272369.4			XP_005272426.2
	XM_005272370.4			XP_005272427.2
	AK122582.1			BAC56923.1
	AL833872.1			CAD38729.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv610154	Chr.8:8244119 - 8470591 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2764098	Chr.8:7102311 - 8743201 on Build GRCh38	Gain+Loss	LOC107986910 PRR23D2 FAM90A7P DEFB4B CLDN23 OR7E154P USP17L1 USP17L3 USP17L4 MIR548I3 DEFB107A DEFB103A LINC00965 FAM90A10P DEFB106B ZNF705B LOC101928095 SPAG11A DEFB109P1B DEFB104A DEFB107B FAM66B OR7E125P DEFB108P1 DEFB103B ZNF705G SGK223 FAM86B3P SPAG11B FAM66E USP17L8 DEFB4A DEFB106A PRR23D1 LOC101929400 DEFB105A DEFB105B DEFB104B
nsv610153	Chr.8:8240557 - 8597021 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2759589	Chr.8:6874198 - 8449233 on Build GRCh38	Gain+Loss	LOC107986910 DEFA1 FAM90A7P DEFB4B DEFA7P FAM90A10P DEFA8P LOC101928095 SPAG11A DEFA4 DEFB109P1B DEFB104A DEFB107B DEFA10P OR7E125P DEFA1B DEFB108P1 DEFB103B ZNF705G SGK223 FAM86B3P DEFB4A LOC101929400 DEFA6 DEFT1P DEFA3 PRR23D2 OR7E154P USP17L1 USP17L3 USP17L4 MIR548I3 DEFB107A DEFB103A LINC00965 DEFA9P DEFB106B ZNF705B DEFA11P DEFB1 DEFT1P2 FAM66B DEFA5 SPAG11B FAM66E USP17L8 DEFB106A PRR23D1 DEFB105A DEFB105B DEFB104B
nsv610156	Chr.8:8305721 - 8349823 on Build GRCh38	Loss	SGK223

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine phosphorylation

Function(s)

protein kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding