Hs03707284_cn

• Gene Symbol: CARD9
• Assay Reference Genome Location: Chr.9:136368612 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 64170
• Gene Name: caspase recruitment domain family member 9
• Gene Aliases: CANDF2, hCARD9
• Location: Chr.9:136363956-136373681 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CARD9	NM_052813.4			NP_434700.2
	NM_052814.3			NP_434701.1
	AF311287.1			AAG28790.1
	AK024001.1			BAB14766.1
	AK127481.1
	AK292081.1
	AK295647.1
	BC008877.2			AAH08877.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831760	Chr.9:136366430 - 136480358 on Build GRCh38	Loss	CARD9 SDCCAG3 PMPCA SNAPC4 INPP5E SEC16A
nsv509333	Chr.9:136346749 - 136440541 on Build GRCh38	Insertion	CARD9 SDCCAG3 GPSM1 PMPCA SNAPC4 INPP5E DNLZ SEC16A
nsv6764	Chr.9:136342675 - 136387661 on Build GRCh38	Deletion	CARD9 GPSM1 SNAPC4 DNLZ
nsv1046074	Chr.9:136228197 - 136393924 on Build GRCh38	Gain	CARD9 GPSM1 LOC101928722 SNAPC4 ESP33 QSOX2 DKFZP434A062 DNLZ CCDC187
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	FAM69B MIR4673 PHPT1 LOC101930307 UAP1L1 MAMDC4 ENTPD2 FBXW5 MIR3621 SNAPC4 LCN10 GRIN1 MIR6722 CARD9 DPP7 NALT1 C8G SAPCD2 ABCA2 INPP5E PRR31 EGFL7 MIR4479 C9orf142 SNHG7 MAN1B1 SNORA17B LINC01451 LCN6 TRAF2 LCN8 DNLZ AGPAT2 LRRC26 PTGDS TMEM141 CCDC183 NPDC1 LCN15 SEC16A TMEM210 MAN1B1-AS1 LCNL1 C9orf172 C9orf139 LOC100128593 MIR4292 SNORA17A FUT7 PMPCA RABL6 NOTCH1 MIR126 SDCCAG3 C9orf163 HSPC324 LCN12 CLIC3 CCDC183-AS1 MIR4674 EDF1
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	FAM69B MIR4673 AGPAT2 TMEM141 CCDC183 PHPT1 MAMDC4 LCN15 SEC16A C9orf172 SNAPC4 LCN10 LOC100128593 MIR6722 CARD9 MIR4292 SNORA17A NALT1 GPSM1 PMPCA RABL6 NOTCH1 MIR126 INPP5E EGFL7 MIR4479 SDCCAG3 SNHG7 SNORA17B C9orf163 HSPC324 LINC01451 LCN6 TRAF2 LCN8 CCDC183-AS1 MIR4674 EDF1 DNLZ
nsv825173	Chr.9:135892081 - 136495763 on Build GRCh38	Gain	LOC107987142 CAMSAP1 CARD9 UBAC1 GPSM1 LOC101928722 PMPCA C9orf69 LHX3 NACC2 DKFZP434A062 NOTCH1 INPP5E CCDC187 LOC105376323 SEC16A SDCCAG3 C9orf163 SNAPC4 ESP33 QSOX2 DNLZ
nsv951202	Chr.9:135770355 - 136558248 on Build GRCh38	Deletion	LOC107987142 MIR4673 KCNT1 NACC2 LOC105376323 SEC16A SNAPC4 CAMSAP1 CARD9 UBAC1 NALT1 GPSM1 LOC101928722 PMPCA C9orf69 LHX3 DKFZP434A062 NOTCH1 INPP5E CCDC187 SDCCAG3 C9orf163 ESP33 QSOX2 MIR4674 DNLZ

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
response to fungus
response to peptidoglycan
response to muramyl dipeptide
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of stress-activated MAPK cascade
response to drug
regulation of tumor necrosis factor biosynthetic process
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
regulation of interleukin-2 biosynthetic process
innate immune response
regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
defense response to virus

Function(s)

protein binding
protein homodimerization activity
CARD domain binding