Hs03729538_cn

• Gene Symbol: HK1
• Assay Reference Genome Location: Chr.10:69280989 on build GRCh38
• Cytoband: 10q22.1

Target Gene Details

• Entrez Gene ID: 3098
• Gene Name: hexokinase 1
• Gene Aliases: HK, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, hexokinase
• Location: Chr.10:69270000-69401882 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HK1	NM_001322364.1			NP_001309293.1
	NM_001322365.1			NP_001309294.1
	NM_033497.2			NP_277032.1
	NM_033498.2			NP_277033.1
	NM_033500.2			NP_277035.2
	XM_011539732.1			XP_011538034.1
	AK128226.1
	DB088955.1
	U38226.1			AAB40527.1
	U38227.1			AAB40528.1
	U38228.1			AAB40529.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3623739	Chr.10:69280069 - 69294203 on Build GRCh38	Loss	HK1
esv2759765	Chr.10:69278961 - 69293132 on Build GRCh38	Loss	HK1
nsv551452	Chr.10:69243856 - 69292752 on Build GRCh38	Loss	HKDC1 HK1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

cellular glucose homeostasis
glycolytic process
glucose transport
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion

Function(s)

glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
mannokinase activity