Hs03766641_cn

• Gene Symbol: CFL1
• Assay Reference Genome Location: Chr.11:65855627 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 1072
• Gene Name: cofilin 1
• Gene Aliases: CFL, HEL-S-15, cofilin
• Location: Chr.11:65854811-65858333 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CFL1	NM_005507.2			NP_005498.1
	AK097690.1
	AK303614.1
	BC011005.2			AAH11005.1
	BC012265.1			AAH12265.1
	BC012318.1			AAH12318.1
	BC018256.2			AAH18256.1
	BT006846.1			AAP35492.1
	CB850882.1
	D00682.1			BAA00589.1
	EU794603.1
	U21909.1			AAA64501.1
	X95404.1			CAA64685.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759834	Chr.11:65792422 - 65954892 on Build GRCh38	Gain	OVOL1 CCDC85B CTSW MUS81 SNX32 DRAP1 CFL1 EFEMP2 FOSL1 C11orf68 TSGA10IP FIBP
nsv555215	Chr.11:65814108 - 65909045 on Build GRCh38	Loss	CCDC85B CTSW MUS81 SNX32 CFL1 EFEMP2 FOSL1 FIBP
nsv1159905	Chr.11:65836608 - 65922038 on Build GRCh38	Duplication	CCDC85B CTSW MUS81 SNX32 DRAP1 CFL1 EFEMP2 FOSL1 C11orf68 FIBP

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

cytoskeleton organization
Rho protein signal transduction
response to virus
regulation of cell morphogenesis
actin cytoskeleton organization
actin filament depolymerization
negative regulation of apoptotic process
positive regulation by host of viral process
regulation of dendritic spine morphogenesis

Function(s)

protein binding
actin filament binding