Hs03794185_cn

• Gene Symbol: TNNT3
• Assay Reference Genome Location: Chr.11:1921156 on build GRCh38
• Cytoband: 11p15.5

Target Gene Details

• Entrez Gene ID: 7140
• Gene Name: troponin T3, fast skeletal type
• Gene Aliases: TNTF
• Location: Chr.11:1919551-1938706 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNNT3	NM_001042780.2			NP_001036245.1
	NM_001042781.2			NP_001036246.1
	NM_001042782.2			NP_001036247.1
	NM_001297646.1			NP_001284575.1
	NM_006757.3			NP_006748.1
	XM_006718290.3			XP_006718353.1
	XM_006718293.2			XP_006718356.1
	XM_006718294.3			XP_006718357.1
	XM_006718296.3			XP_006718359.1
	XM_006718299.2			XP_006718362.1
	XM_006718300.3			XP_006718363.1
	XM_006718302.3			XP_006718365.1
	XM_017018205.1			XP_016873694.1
	XM_017018206.1			XP_016873695.1
	XM_017018207.1			XP_016873696.1
	XM_017018209.1			XP_016873698.1
	XM_017018211.1			XP_016873700.1
	XM_017018216.1			XP_016873705.1
	XM_017018217.1			XP_016873706.1
	XM_017018218.1			XP_016873707.1
	XM_017018219.1			XP_016873708.1
	BC050446.1			AAH50446.1
	BC062430.1			AAH62430.1
	BX640689.1			CAE45814.1
	DA897990.1
	DA899275.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522320	Chr.11:1835882 - 1996938 on Build GRCh38	Loss	LINC01219 MRPL23-AS1 TNNI2 LSP1 MIR7847 TNNT3 LINC01150 HOTS MIR4298 MRPL23 SYT8 SNORD131 H19 MIR675
nsv1047474	Chr.11:1803515 - 2043381 on Build GRCh38	Gain	LINC01219 MRPL23-AS1 TNNI2 LSP1 MIR7847 TNNT3 LINC01150 HOTS MIR4298 MRPL23 SYT8 SNORD131 H19 MIR675
nsv1039289	Chr.11:1883459 - 1939958 on Build GRCh38	Gain	LINC01150 LSP1 TNNT3
nsv469926	Chr.11:1813024 - 2036416 on Build GRCh38	Loss	LINC01219 MRPL23-AS1 TNNI2 LSP1 MIR7847 TNNT3 LINC01150 HOTS MIR4298 MRPL23 SYT8 SNORD131 H19 MIR675
dgv132e201	Chr.11:1894328 - 1939803 on Build GRCh38	Deletion	LINC01150 TNNT3
nsv7643	Chr.11:1867726 - 1927695 on Build GRCh38	Deletion	LINC01150 LSP1 MIR7847 TNNT3
nsv951283	Chr.11:1913571 - 2040070 on Build GRCh38	Deletion	LINC01219 MRPL23-AS1 HOTS MRPL23 SNORD131 H19 MIR675 TNNT3
esv29980	Chr.11:1820597 - 2097889 on Build GRCh38	Loss	LINC01219 MRPL23-AS1 TNNI2 LSP1 MIR7847 TNNT3 LINC01150 HOTS MIR4298 MRPL23 SYT8 SNORD131 H19 MIR675
nsv553047	Chr.11:1733170 - 2418537 on Build GRCh38	Gain	INS-IGF2 MRPL23-AS1 MIR4686 IFITM10 HOTS CD81-AS1 CD81 MIR4298 MIR483 ASCL2 SYT8 CTSD TSPAN32 LINC01219 IGF2-AS C11orf21 TRPM5 TNNI2 TH IGF2 TSSC4 LSP1 MIR7847 TNNT3 LINC01150 MRPL23 INS SNORD131 H19 MIR675

More Information

Additional Information:

For this assay, SNP(s) [rs73413015] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

actin binding motor protein

Gene Ontology Categories:

Process(es)

skeletal muscle contraction
regulation of striated muscle contraction
muscle filament sliding
regulation of ATPase activity

Function(s)

actin binding
tropomyosin binding
troponin C binding
calcium-dependent ATPase activity
troponin I binding
calcium-dependent protein binding