Hs03806810_cn

• Gene Symbol: LTBR
• Assay Reference Genome Location: Chr.12:6386055 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 4055
• Gene Name: lymphotoxin beta receptor
• Gene Aliases: CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3
• Location: Chr.12:6375368-6391571 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LTBR	NM_001270987.1			NP_001257916.1
	NM_002342.2			NP_002333.1
	XM_005253688.1			XP_005253745.1
	XM_006718983.2			XP_006719046.1
	AK027080.1
	AK095418.1
	AK293187.1
	BC026262.1			AAH26262.1
	L04270.1			AAA36757.1
	L04489.1	1	234

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952790	Chr.12:6368835 - 6394034 on Build GRCh38	Deletion	SCNN1A LTBR
esv34325	Chr.12:6342424 - 6513183 on Build GRCh38	Gain	CD27 SCARNA10 SCNN1A VAMP1 CD27-AS1 LTBR MRPL51 NCAPD2 TAPBPL
esv2759876	Chr.12:6344718 - 6554669 on Build GRCh38	Gain	CD27 SCARNA10 SCNN1A GAPDH VAMP1 CD27-AS1 LTBR MRPL51 IFFO1 NCAPD2 TAPBPL

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
inflammatory response
immune response
signal transduction
multicellular organism development
viral process
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
myeloid dendritic cell differentiation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JNK cascade
cellular response to mechanical stimulus
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

tumor necrosis factor-activated receptor activity
protein binding
ubiquitin protein ligase binding
identical protein binding