Hs03826325_cn

• Gene Symbol: LTBR
• Assay Reference Genome Location: Chr.12:6378950 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 4055
• Gene Name: lymphotoxin beta receptor
• Gene Aliases: CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3
• Location: Chr.12:6375368-6391571 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LTBR	NM_001270987.1			NP_001257916.1
	AK293187.1
	DC424721.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952790	Chr.12:6368835 - 6394034 on Build GRCh38	Deletion	LTBR SCNN1A
esv34325	Chr.12:6342424 - 6513183 on Build GRCh38	Gain	CD27-AS1 SCARNA10 CD27 MRPL51 TAPBPL LTBR NCAPD2 VAMP1 SCNN1A
esv2759876	Chr.12:6344718 - 6554669 on Build GRCh38	Gain	CD27-AS1 SCARNA10 CD27 MRPL51 TAPBPL LTBR GAPDH IFFO1 NCAPD2 VAMP1 SCNN1A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
inflammatory response
immune response
signal transduction
multicellular organism development
viral process
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
myeloid dendritic cell differentiation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JNK cascade
cellular response to mechanical stimulus
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

tumor necrosis factor-activated receptor activity
protein binding
ubiquitin protein ligase binding
identical protein binding