Hs03894747_cn

• Gene Symbol: ITPKA
• Assay Reference Genome Location: Chr.15:41499236 on build GRCh38
• Cytoband: 15q15.1

Target Gene Details

• Entrez Gene ID: 3706
• Gene Name: inositol-trisphosphate 3-kinase A
• Gene Aliases: IP3-3KA, IP3KA
• Location: Chr.15:41493858-41503559 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ITPKA	NM_002220.2			NP_002211.1
	XM_011521522.2			XP_011519824.1
	BC026331.1			AAH26331.1
	X54938.1			CAA38700.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471241	Chr.15:41491616 - 41528002 on Build GRCh38	Loss	LTK RPAP1 ITPKA
esv33378	Chr.15:41494307 - 41513562 on Build GRCh38	Gain	LTK ITPKA
nsv524476	Chr.15:41397034 - 41528002 on Build GRCh38	Loss	LTK NDUFAF1 RPAP1 RTF1 ITPKA
nsv569233	Chr.15:41492611 - 41513039 on Build GRCh38	Loss	LTK ITPKA

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

inositol metabolic process
protein phosphorylation
signal transduction
actin cytoskeleton organization
inositol phosphate metabolic process
regulation of synaptic plasticity
positive regulation of dendritic spine morphogenesis
dendritic spine maintenance

Function(s)

calmodulin-dependent protein kinase activity
calmodulin binding
ATP binding
inositol-1,4,5-trisphosphate 3-kinase activity
Rac GTPase binding