Hs03899350_cn

• Gene Symbol: CYP19A1
• Assay Reference Genome Location: Chr.15:51219949 on build GRCh38
• Cytoband: 15q21.2

Target Gene Details

• Entrez Gene ID: 1588
• Gene Name: cytochrome P450 family 19 subfamily A member 1
• Gene Aliases: ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
• Location: Chr.15:51208057-51338598 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP19A1	NM_000103.3			NP_000094.2
	NM_031226.2			NP_112503.1
	XM_005254191.1			XP_005254248.1
	AK291778.1
	BC020767.1
	BC022896.1			AAH22896.1
	BC035959.1			AAH35959.1
	BC056258.1			AAH56258.1
	BC107785.1			AAI07786.1
	DQ118405.1			AAZ23558.1
	J04127.1			AAA52132.1
	M18856.1			AAA35556.1
	M22246.1			AAA35557.1
	M28420.1			AAA52141.1
	X13589.1			CAA31929.1
	Y07508.1			CAA68807.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3636461	Chr.15:51022583 - 51482654 on Build GRCh38	Gain	MIR7973-1 GLDN TNFAIP8L3 MIR7973-2 CYP19A1 DMXL2 MIR4713 PIRC66
nsv471243	Chr.15:51053288 - 51725899 on Build GRCh38	Gain	MIR7973-1 GLDN TNFAIP8L3 LYSMD2 MIR7973-2 CYP19A1 DMXL2 MIR4713 SCG3 PIRC66
nsv1047443	Chr.15:50452584 - 51354826 on Build GRCh38	Gain	SPPL2A AP4E1 MIR4713 MIR7973-1 GLDN DCAF13P3 TNFAIP8L3 MIR7973-2 USP50 CYP19A1 USP8 TRPM7 PIRC66
esv34532	Chr.15:50983931 - 51460659 on Build GRCh38	Gain	MIR7973-1 GLDN TNFAIP8L3 MIR7973-2 CYP19A1 DMXL2 AP4E1 MIR4713 PIRC66
esv2760031	Chr.15:50990060 - 51538142 on Build GRCh38	Gain	MIR7973-1 GLDN TNFAIP8L3 MIR7973-2 CYP19A1 DMXL2 AP4E1 MIR4713 PIRC66
dgv4526n54	Chr.15:50582767 - 51475068 on Build GRCh38	Gain	MIR7973-1 GLDN DCAF13P3 TNFAIP8L3 MIR7973-2 CYP19A1 DMXL2 SPPL2A TRPM7 AP4E1 MIR4713 PIRC66

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

negative regulation of chronic inflammatory response
steroid biosynthetic process
estrogen biosynthetic process
androgen metabolic process
negative regulation of macrophage chemotaxis
sterol metabolic process
oxidation-reduction process
prostate gland growth

Function(s)

iron ion binding
steroid hydroxylase activity
electron carrier activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
aromatase activity