Hs03914578_cn

• Gene Symbol: CYP19A1
• Assay Reference Genome Location: Chr.15:51213342 on build GRCh38
• Cytoband: 15q21.2

Target Gene Details

• Entrez Gene ID: 1588
• Gene Name: cytochrome P450 family 19 subfamily A member 1
• Gene Aliases: ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
• Location: Chr.15:51208057-51338598 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP19A1	NM_000103.3			NP_000094.2
	NM_031226.2			NP_112503.1
	XM_005254191.1			XP_005254248.1
	AK291778.1
	BC020767.1
	BC022896.1			AAH22896.1
	BC035959.1			AAH35959.1
	BC056258.1			AAH56258.1
	BC107785.1			AAI07786.1
	DQ118405.1			AAZ23558.1
	J04127.1			AAA52132.1
	M18856.1			AAA35556.1
	M22246.1			AAA35557.1
	M28420.1			AAA52141.1
	X13589.1			CAA31929.1
	Y07508.1			CAA68807.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3636461	Chr.15:51022583 - 51482654 on Build GRCh38	Gain	PIRC66 DMXL2 MIR7973-2 MIR4713 TNFAIP8L3 MIR7973-1 CYP19A1 GLDN
nsv471243	Chr.15:51053288 - 51725899 on Build GRCh38	Gain	PIRC66 DMXL2 MIR7973-2 MIR4713 LYSMD2 TNFAIP8L3 MIR7973-1 CYP19A1 GLDN SCG3
nsv1047443	Chr.15:50452584 - 51354826 on Build GRCh38	Gain	PIRC66 MIR7973-2 DCAF13P3 SPPL2A AP4E1 USP50 TNFAIP8L3 TRPM7 USP8 CYP19A1 GLDN MIR4713 MIR7973-1
esv34532	Chr.15:50983931 - 51460659 on Build GRCh38	Gain	PIRC66 DMXL2 MIR7973-2 MIR4713 AP4E1 TNFAIP8L3 MIR7973-1 CYP19A1 GLDN
esv2760031	Chr.15:50990060 - 51538142 on Build GRCh38	Gain	PIRC66 DMXL2 MIR7973-2 MIR4713 AP4E1 TNFAIP8L3 MIR7973-1 CYP19A1 GLDN
dgv4526n54	Chr.15:50582767 - 51475068 on Build GRCh38	Gain	PIRC66 DMXL2 MIR7973-2 MIR4713 DCAF13P3 SPPL2A AP4E1 TNFAIP8L3 TRPM7 MIR7973-1 CYP19A1 GLDN

More Information

Additional Information:

For this assay, SNP(s) [rs549165695] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

negative regulation of chronic inflammatory response
steroid biosynthetic process
estrogen biosynthetic process
androgen metabolic process
negative regulation of macrophage chemotaxis
sterol metabolic process
oxidation-reduction process
prostate gland growth

Function(s)

iron ion binding
steroid hydroxylase activity
electron carrier activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
aromatase activity