Hs03919425_cn

• Gene Symbol: LOC105371419
• Assay Reference Genome Location: Chr.16:89851193 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 105371419
• Gene Name: uncharacterized LOC105371419
• Gene Aliases: -
• Location: Chr.16:89846857-89854277 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105371419	XM_011523522.2			XP_011521824.1

Target Gene Details

• Entrez Gene ID: 84501
• Gene Name: spire type actin nucleation factor 2
• Gene Aliases: Spir-2
• Location: Chr.16:89817477-89871319 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPIRE2	NM_032451.1			NP_115827.1
	XM_011523379.1			XP_011521681.1
	XM_011523380.2			XP_011521682.1
	XM_011523381.1			XP_011521683.1
	XM_011523384.1			XP_011521686.1
	XM_011523385.1			XP_011521687.1
	XM_017023779.1			XP_016879268.1
	XM_017023780.1			XP_016879269.1
	XM_017023781.1			XP_016879270.1
	AB058735.1			BAB47461.1
	AJ422077.1			CAD19439.1
	AL834408.1			CAD39070.1
	BC111030.1			AAI11031.1
	BC139732.1
	BX439688.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv573744	Chr.16:89738447 - 89915950 on Build GRCh38	Loss	LOC107984817 ZNF276 SPIRE2 FANCA TCF25 LOC105371419
esv3639601	Chr.16:89845985 - 89862110 on Build GRCh38	Loss	SPIRE2 LOC105371419
esv2758671	Chr.16:89804324 - 89901541 on Build GRCh38	Loss	LOC107984817 SPIRE2 FANCA TCF25 LOC105371419
nsv573743	Chr.16:89664419 - 89853617 on Build GRCh38	Gain	CDK10 LOC107984817 ZNF276 SPIRE2 FANCA SPATA2L VPS9D1-AS1 VPS9D1 SPATA33 LOC105371419
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	CDK10 LOC107984817 AFG3L1P GAS8-AS1 VPS9D1-AS1 DEF8 TUBB3 VPS9D1 SPATA33 LOC105371419 CHMP1A ZNF276 SPIRE2 GAS8 FANCA SPATA2L MC1R DPEP1 TCF25 CENPBD1 DBNDD1
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	LOC107984817 URAHP AFG3L1P VPS9D1-AS1 PRDM7 TUBB3 SNORD68 LOC105371414 CHMP1A SPIRE2 GAS8 SPATA2L TUBB8P7 TCF25 CENPBD1 DBNDD1 CPNE7 ANKRD11 ZNF778 CDK10 FAM157C GAS8-AS1 DEF8 RPL13 VPS9D1 SPG7 SPATA33 LOC105371419 LOC100287036 ZNF276 FANCA MC1R DPEP1 LOC101927817
dgv5330n54	Chr.16:89851129 - 89852857 on Build GRCh38	Loss	SPIRE2 LOC105371419
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	GALNS LOC107984817 URAHP AFG3L1P VPS9D1-AS1 TUBB3 SNORD68 CHMP1A LOC100289580 SPIRE2 CYBA CDT1 TUBB8P7 LOC339059 TCF25 CENPBD1 ANKRD11 FAM157C LOC400558 TRAPPC2L MVD PIEZO1 GAS8-AS1 LINC00304 LOC107987238 DEF8 SPATA33 MC1R DPEP1 APRT SNAI3-AS1 LOC100129697 CDH15 SLC22A31 PRDM7 MIR4722 LOC105371414 GAS8 CBFA2T3 SPATA2L DBNDD1 CPNE7 CTU2 ZNF778 LOC101927793 CDK10 RPL13 VPS9D1 SPG7 LOC105371419 LOC100287036 RNF166 PABPN1L IL17C SNAI3 ZNF276 FANCA LOC105371409 LOC101927817 ACSF3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

protein transport
vesicle-mediated transport
actin cytoskeleton organization
cleavage furrow formation
polar body extrusion after meiotic divisions
actin nucleation
intracellular transport
establishment of meiotic spindle localization
formin-nucleated actin cable assembly

Function(s)

actin binding