Hs03926726_cn

• Gene Symbol: MIR5189
• Assay Reference Genome Location: Chr.16:88469066 on build GRCh38
• Cytoband: 16q24.2

Target Gene Details

• Entrez Gene ID: 100847057
• Gene Name: microRNA 5189
• Gene Aliases: mir-5189
• Location: Chr.16:88468918-88469031 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR5189	NR_049821.1

Target Gene Details

• Entrez Gene ID: 161882
• Gene Name: zinc finger protein, FOG family member 1
• Gene Aliases: FOG, FOG1, ZC2HC11A, ZNF408, ZNF89A
• Location: Chr.16:88451782-88535166 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZFPM1	NM_153813.2			NP_722520.2
	XM_011522914.2			XP_011521216.1
	AF488691.1			AAN45858.1
	BE219988.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528456	Chr.16:88321646 - 88485962 on Build GRCh38	Loss	ZFPM1 MIR5189 ZNF469
dgv5293n54	Chr.16:88387351 - 88485962 on Build GRCh38	Loss	ZFPM1 MIR5189 ZNF469
nsv471112	Chr.16:88397812 - 88485962 on Build GRCh38	Gain	ZFPM1 MIR5189 ZNF469
esv2758669	Chr.16:88392764 - 88543508 on Build GRCh38	Gain	ZFPM1 MIR5189 ZNF469
dgv171n21	Chr.16:88382277 - 88503975 on Build GRCh38	Loss	ZFPM1 MIR5189 ZNF469
nsv471111	Chr.16:88298034 - 88503975 on Build GRCh38	Loss	ZFPM1 MIR5189 ZNF469
nsv1061590	Chr.16:88228010 - 88560181 on Build GRCh38	Gain	LOC107984862 ZFPM1 ZC3H18-AS1 MIR5189 ZNF469
nsv817747	Chr.16:88460415 - 88488151 on Build GRCh38	Loss	ZFPM1 MIR5189
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	LOC107984862 ZC3H18 ZC3H18-AS1 MIR5189 ZNF469 CYBA PIEZO1 IL17C RNF166 LOC339059 MIR4722 SNAI3-AS1 ZFPM1 CTU2 LOC100289580 MVD SNAI3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
T-helper cell lineage commitment
outflow tract morphogenesis
atrioventricular valve morphogenesis
mitral valve formation
tricuspid valve formation
transcription, DNA-templated
heart development
blood coagulation
regulation of definitive erythrocyte differentiation
erythrocyte differentiation
megakaryocyte differentiation
platelet formation
granulocyte differentiation
negative regulation of protein binding
regulation of chemokine production
embryonic hemopoiesis
megakaryocyte development
positive regulation of interferon-gamma biosynthetic process
negative regulation of interleukin-4 biosynthetic process
negative regulation of fat cell differentiation
cardiac muscle tissue morphogenesis
definitive erythrocyte differentiation
primitive erythrocyte differentiation
negative regulation of mast cell differentiation
ventricular septum morphogenesis
atrial septum morphogenesis
transcriptional activation by promoter-enhancer looping

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
protein binding
transcription factor binding
metal ion binding