Hs03942780_cn

• Gene Symbol: LOC105371419
• Assay Reference Genome Location: Chr.16:89850761 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 105371419
• Gene Name: uncharacterized LOC105371419
• Gene Aliases: -
• Location: Chr.16:89846857-89854277 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105371419	XM_011523522.2			XP_011521824.1

Target Gene Details

• Entrez Gene ID: 84501
• Gene Name: spire type actin nucleation factor 2
• Gene Aliases: Spir-2
• Location: Chr.16:89817477-89871319 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPIRE2	NM_032451.1			NP_115827.1
	XM_011523379.1			XP_011521681.1
	XM_011523380.2			XP_011521682.1
	XM_011523381.1			XP_011521683.1
	XM_011523384.1			XP_011521686.1
	XM_011523385.1			XP_011521687.1
	XM_017023779.1			XP_016879268.1
	XM_017023780.1			XP_016879269.1
	XM_017023781.1			XP_016879270.1
	AB058735.1			BAB47461.1
	AJ422077.1			CAD19439.1
	AL834408.1			CAD39070.1
	BC111030.1			AAI11031.1
	BC139732.1
	BX439688.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv573744	Chr.16:89738447 - 89915950 on Build GRCh38	Loss	TCF25 FANCA SPIRE2 LOC105371419 ZNF276 LOC107984817
esv3639601	Chr.16:89845985 - 89862110 on Build GRCh38	Loss	SPIRE2 LOC105371419
esv2758671	Chr.16:89804324 - 89901541 on Build GRCh38	Loss	TCF25 FANCA SPIRE2 LOC105371419 LOC107984817
nsv573743	Chr.16:89664419 - 89853617 on Build GRCh38	Gain	VPS9D1-AS1 SPATA33 FANCA SPIRE2 VPS9D1 LOC105371419 SPATA2L ZNF276 CDK10 LOC107984817
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	FANCA SPIRE2 VPS9D1 TUBB3 DPEP1 GAS8-AS1 GAS8 DBNDD1 VPS9D1-AS1 SPATA33 TCF25 MC1R LOC105371419 AFG3L1P SPATA2L ZNF276 DEF8 CHMP1A CDK10 LOC107984817 CENPBD1
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	SPIRE2 CPNE7 TUBB3 TUBB8P7 GAS8 SNORD68 DBNDD1 VPS9D1-AS1 TCF25 FAM157C ZNF778 MC1R URAHP DEF8 CHMP1A CENPBD1 FANCA VPS9D1 DPEP1 GAS8-AS1 ANKRD11 LOC101927817 LOC100287036 LOC105371414 SPATA33 SPG7 LOC105371419 RPL13 AFG3L1P SPATA2L ZNF276 PRDM7 CDK10 LOC107984817
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC100289580 RNF166 SPIRE2 CPNE7 TUBB3 TUBB8P7 SNORD68 SNAI3-AS1 DBNDD1 MIR4722 APRT TCF25 FAM157C CDH15 ZNF778 PABPN1L MC1R CHMP1A CENPBD1 FANCA ACSF3 ANKRD11 LINC00304 CBFA2T3 PIEZO1 LOC105371414 TRAPPC2L LOC400558 SPG7 AFG3L1P PRDM7 CDK10 LOC107984817 CYBA MVD CTU2 GAS8 VPS9D1-AS1 SLC22A31 URAHP DEF8 LOC105371409 VPS9D1 SNAI3 IL17C DPEP1 GAS8-AS1 LOC107987238 LOC100129697 CDT1 LOC101927817 LOC100287036 SPATA33 LOC105371419 LOC101927793 LOC339059 RPL13 SPATA2L ZNF276 GALNS

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

protein transport
vesicle-mediated transport
actin cytoskeleton organization
cleavage furrow formation
polar body extrusion after meiotic divisions
actin nucleation
intracellular transport
establishment of meiotic spindle localization
formin-nucleated actin cable assembly

Function(s)

actin binding