Hs03943202_cn

• Gene Symbol: CORO1A
• Assay Reference Genome Location: Chr.16:30184271 on build GRCh38
• Cytoband: 16p11.2

Target Gene Details

• Entrez Gene ID: 11151
• Gene Name: coronin 1A
• Gene Aliases: CLABP, CLIPINA, HCORO1, IMD8, TACO, p57
• Location: Chr.16:30183410-30189076 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CORO1A	NM_001193333.2			NP_001180262.1
	NM_007074.3			NP_009005.1
	XM_011545714.2			XP_011544016.1
	XM_017022885.1			XP_016878374.1
	XM_017022886.1			XP_016878375.1
	AB209221.1			BAD92458.1
	AF495470.1			AAM18516.1
	AK096332.1
	AK296207.1
	AK314714.1
	BC110374.1			AAI10375.1
	BC126385.1
	BC126387.1
	CD623635.1
	D44497.1			BAA07940.1
	DA256300.1
	DC408372.1
	U34690.1			AAA77058.1
	X89109.1			CAA61482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9431	Chr.16:30179216 - 30218525 on Build GRCh38	Gain+Loss	SULT1A3 CORO1A LOC613038 SLX1A-SULT1A3 BOLA2B SLX1A
nsv571819	Chr.16:30147436 - 30204300 on Build GRCh38	Gain	SULT1A3 CORO1A SLX1A-SULT1A3 BOLA2B SLX1A
esv2758642	Chr.16:30062634 - 30371959 on Build GRCh38	Gain	LOC107983970 SULT1A3 LOC613038 MAPK3 BOLA2B SLX1A MYLPF TBX6 ALDOA CD2BP2 LOC101928595 LOC613037 SMG1P5 TBC1D10B YPEL3 CORO1A PPP4C SLX1A-SULT1A3 GDPD3

More Information

Additional Information:

For this assay, SNP(s) [rs116307333] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

immunological synapse formation
phagolysosome assembly
calcium ion transport
phagocytosis
movement of cell or subcellular component
actin filament organization
regulation of cell shape
actin cytoskeleton organization
positive regulation of cell migration
leukocyte chemotaxis
negative regulation of vesicle fusion
cell-substrate adhesion
uropod organization
regulation of actin cytoskeleton organization
nerve growth factor signaling pathway
positive regulation of T cell proliferation
T cell homeostasis
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
homeostasis of number of cells within a tissue
positive chemotaxis
negative regulation of actin nucleation
regulation of release of sequestered calcium ion into cytosol
early endosome to recycling endosome transport
cellular response to interleukin-4

Function(s)

actin binding
actin monomer binding
protein binding
protein C-terminus binding
cytoskeletal protein binding
myosin heavy chain binding
protein homodimerization activity
phosphatidylinositol 3-kinase binding
poly(A) RNA binding
actin filament binding