Hs03955059_cn

• Gene Symbol: RBFOX3
• Assay Reference Genome Location: Chr.17:79092822 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 146713
• Gene Name: RNA binding protein, fox-1 homolog 3
• Gene Aliases: FOX-3, FOX3, HRNBP3, NEUN
• Location: Chr.17:79089345-79611101 on Build GRCh38
• Assay Gene Location: Within Intron 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RBFOX3	NM_001082575.2			NP_001076044.1
	XM_011524359.1			XP_011522661.1
	XM_011524360.1			XP_011522662.1
	XM_011524362.2			XP_011522664.1
	XM_011524363.2			XP_011522665.1
	XM_011524365.2			XP_011522667.1
	XM_011524366.2			XP_011522668.1
	XM_011524367.2			XP_011522669.1
	XM_017024208.1			XP_016879697.1
	XM_017024209.1			XP_016879698.1
	XM_017024210.1			XP_016879699.1
	XM_017024211.1			XP_016879700.1
	AK124644.1
	AK128131.1
	AK293617.1
	BM714144.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833556	Chr.17:79037891 - 79221474 on Build GRCh38	Loss	RBFOX3 C1QTNF1 ENGASE
nsv952379	Chr.17:79054919 - 79342518 on Build GRCh38	Deletion	RBFOX3 ENGASE
nsv523650	Chr.17:78933797 - 79165563 on Build GRCh38	Loss	RBFOX3 C1QTNF1-AS1 C1QTNF1 ENGASE CANT1 LGALS3BP
nsv1057193	Chr.17:78921031 - 79481744 on Build GRCh38	Gain	RBFOX3 C1QTNF1-AS1 TIMP2 C1QTNF1 ENGASE CANT1 LGALS3BP
nsv527899	Chr.17:79085706 - 79165563 on Build GRCh38	Loss	RBFOX3 ENGASE
nsv2157	Chr.17:79074896 - 79105704 on Build GRCh38	Insertion	RBFOX3 ENGASE

More Information

Additional Information:

For this assay, SNP(s) [rs114378137] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA processing factor, RNA splicing factor, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

regulation of alternative mRNA splicing, via spliceosome
mRNA processing
RNA splicing

Function(s)

nucleotide binding
DNA binding
mRNA binding