Hs03974872_cn

• Gene Symbol: KPNB1
• Assay Reference Genome Location: Chr.17:47649817 on build GRCh38
• Cytoband: 17q21.32

Target Gene Details

• Entrez Gene ID: 3837
• Gene Name: karyopherin subunit beta 1
• Gene Aliases: IMB1, IPO1, IPOB, Impnb, NTF97
• Location: Chr.17:47649838-47683638 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KPNB1	NM_002265.5			NP_002256.2
	AK316421.1	1	342
	DB083013.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525267	Chr.17:47374528 - 47658340 on Build GRCh38	Gain	NPEPPS KPNB1 MRPL45P2 EFCAB13
esv2758693	Chr.17:47443008 - 47687590 on Build GRCh38	Gain+Loss	NPEPPS KPNB1 MRPL45P2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transporter

Gene Ontology Categories:

Process(es)

protein import into nucleus, docking
protein import into nucleus, translocation
apoptotic DNA fragmentation
protein import into nucleus
NLS-bearing protein import into nucleus
ribosomal protein import into nucleus
mitotic chromosome movement towards spindle pole
mitotic metaphase plate congression
modulation by virus of host process
astral microtubule organization
Ran protein signal transduction
establishment of mitotic spindle localization
establishment of protein localization
intracellular transport of virus
mitotic spindle assembly

Function(s)

protein binding
nuclear localization sequence binding
zinc ion binding
Ran GTPase binding
protein transporter activity
enzyme binding
protein domain specific binding
poly(A) RNA binding
Hsp90 protein binding