Hs03992654_cn

• Gene Symbol: FECH
• Assay Reference Genome Location: Chr.18:57561555 on build GRCh38
• Cytoband: 18q21.31

Target Gene Details

• Entrez Gene ID: 2235
• Gene Name: ferrochelatase
• Gene Aliases: EPP, FCE
• Location: Chr.18:57544841-57586737 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FECH	NM_000140.3			NP_000131.2
	NM_001012515.2			NP_001012533.1
	XM_011525881.1			XP_011524183.1
	XM_011525882.2			XP_011524184.1
	XM_017025614.1			XP_016881103.1
	AK092416.1			BAC03882.1
	AK223190.1			BAD96910.1
	AK292937.1
	AK299643.1
	BC039841.1			AAH39841.2
	BT019958.1			AAV38761.1
	BT019959.1			AAV38762.1
	BX571744.1			CAE11869.1
	D00726.1			BAA00628.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833663	Chr.18:57549030 - 57718589 on Build GRCh38	Gain	FECH LOC100505549 ATP8B1 NARS
nsv577032	Chr.18:57517516 - 57756707 on Build GRCh38	Gain	FECH LOC100505549 ATP8B1 NARS
esv2751777	Chr.18:57515803 - 57805084 on Build GRCh38	Gain	FECH LOC100505549 ATP8B1 NARS

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase

Gene Ontology Categories:

Process(es)

generation of precursor metabolites and energy
heme biosynthetic process
response to light stimulus
response to lead ion
response to insecticide
response to drug
response to ethanol
protoporphyrinogen IX metabolic process
response to arsenic-containing substance
response to methylmercury
response to platinum ion
cellular response to dexamethasone stimulus

Function(s)

ferrochelatase activity
protein binding
ferrous iron binding
2 iron, 2 sulfur cluster binding