Hs04017762_cn

• Gene Symbol: PLPP2
• Assay Reference Genome Location: Chr.19:289927 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 8612
• Gene Name: phospholipid phosphatase 2
• Gene Aliases: LPP2, PAP-2c, PAP2-g, PPAP2C
• Location: Chr.19:281040-291435 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLPP2	NM_003712.3			NP_003703.1
	NM_177526.2			NP_803545.1
	NM_177543.2			NP_808211.1
	XM_011528396.2			XP_011526698.1
	AF035959.1			AAC15968.1
	AF047760.1			AAC32104.1
	AF056083.1			AAC25666.1
	BC002806.2			AAH02806.1
	BE615792.1
	BG831889.1
	BM050291.1
	BT007021.1			AAP35667.1
	HY160303.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833702	Chr.19:238657 - 402129 on Build GRCh38	Loss	THEG MIER2 PLPP2 LOC101929060
nsv953937	Chr.19:276901 - 301700 on Build GRCh38	Deletion	PLPP2 LOC101929060
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	SHC2 POLRMT THEG MIER2 BSG HCN2 CDC34 C2CD4C GZMM LOC101929060 PRSS57 FSTL3 ODF3L2 RNF126 PLPP2 TPGS1 MADCAM1 FGF22
dgv3419n100	Chr.19:90898 - 305459 on Build GRCh38	Gain	LINC01002 PLPP2 OR4F17 LOC101929060
esv3643342	Chr.19:266428 - 341459 on Build GRCh38	Gain	MIER2 PLPP2 LOC101929060
esv3643344	Chr.19:286841 - 307454 on Build GRCh38	Gain	MIER2 PLPP2 LOC101929060
nsv1058440	Chr.19:255818 - 301668 on Build GRCh38	Gain	PLPP2 LOC101929060
esv2422333	Chr.19:251718 - 404517 on Build GRCh38	Duplication	THEG MIER2 PLPP2 LOC101929060
esv2763195	Chr.19:90910 - 296458 on Build GRCh38	Gain	LINC01002 PLPP2 OR4F17

More Information

Additional Information:

For this assay, SNP(s) [rs114778907] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

protein dephosphorylation
phospholipid metabolic process
signal transduction
sphingolipid biosynthetic process
phospholipid dephosphorylation

Function(s)

phosphoprotein phosphatase activity
protein binding
phosphatidate phosphatase activity
sphingosine-1-phosphate phosphatase activity
lipid phosphatase activity