Hs04034295_cn

• Gene Symbol: SLCO4A1
• Assay Reference Genome Location: Chr.20:62649563 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 28231
• Gene Name: solute carrier organic anion transporter family member 4A1
• Gene Aliases: OATP-E, OATP1, OATP4A1, OATPE, OATPRP1, POAT, SLC21A12
• Location: Chr.20:62642445-62690700 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLCO4A1	NM_016354.3			NP_057438.3
	XM_005260203.2			XP_005260260.1
	XM_011528792.2			XP_011527094.1
	XM_017027826.1			XP_016883315.1
	XM_017027827.1			XP_016883316.1
	AF104334.1			AAF15545.1
	AF205072.1			AAG42204.1
	AK023410.1			BAB14566.1
	BC015727.1			AAH15727.1
	BM846201.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422398	Chr.20:62207833 - 62674040 on Build GRCh38	Duplication	RBBP8NL RPS21 LAMA5 HRH3 ADRM1 LOC105369209 C20orf166-AS1 SLCO4A1-AS1 LAMA5-AS1 MIR1-1HG SLCO4A1 CABLES2 MIR133A2 MIR1-1 MIR4758 OSBPL2 GATA5
nsv834026	Chr.20:62636291 - 62795287 on Build GRCh38	Loss	SLCO4A1 LINC00659 LOC107985428 NTSR1 LOC107987285 SLCO4A1-AS1
nsv586496	Chr.20:62332390 - 62812195 on Build GRCh38	Gain	OGFR RBBP8NL RPS21 NTSR1 LAMA5 LOC107987285 C20orf166-AS1 SLCO4A1-AS1 LAMA5-AS1 MIR1-1HG MRGBP SLCO4A1 CABLES2 MIR133A2 LINC00659 LOC107985428 OGFR-AS1 MIR1-1 MIR4758 GATA5
nsv586503	Chr.20:62645662 - 62776055 on Build GRCh38	Gain	SLCO4A1 LINC00659 LOC107985428 NTSR1 LOC107987285 SLCO4A1-AS1
nsv953302	Chr.20:62345345 - 62831248 on Build GRCh38	Deletion	OGFR RBBP8NL RPS21 NTSR1 LAMA5 LOC107987285 C20orf166-AS1 SLCO4A1-AS1 LAMA5-AS1 COL9A3 MIR1-1HG MRGBP SLCO4A1 CABLES2 MIR133A2 LINC00659 LOC107985428 OGFR-AS1 MIR1-1 GATA5
nsv428380	Chr.20:62632018 - 62935383 on Build GRCh38	Loss	OGFR NTSR1 LOC107987285 SLCO4A1-AS1 COL9A3 DPH3P1 MRGBP SLCO4A1 LINC00659 LOC107985428 OGFR-AS1 TCFL5 DIDO1

More Information

Additional Information:

For this assay, SNP(s) [rs73145463] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transporter

Gene Ontology Categories:

Process(es)

thyroid hormone metabolic process
sodium-independent organic anion transport
thyroid hormone transport

Function(s)

sodium-independent organic anion transmembrane transporter activity
thyroid hormone transmembrane transporter activity