Hs04036998_cn

• Gene Symbol: SIRPB1
• Assay Reference Genome Location: Chr.20:1618145 on build GRCh38
• Cytoband: 20p13

Target Gene Details

• Entrez Gene ID: 10326
• Gene Name: signal regulatory protein beta 1
• Gene Aliases: CD172b, SIRP-BETA-1
• Location: Chr.20:1564193-1620457 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIRPB1	XM_011529130.2			XP_011527432.1
	XM_011529134.2			XP_011527436.1
	XM_017027577.1			XP_016883066.1
	XM_017027578.1			XP_016883067.1
	XM_017027579.1			XP_016883068.1
	XM_017027580.1			XP_016883069.1
	XM_017027581.1			XP_016883070.1
	XM_017027582.1			XP_016883071.1
	XM_017027583.1			XP_016883072.1
	XM_017027584.1			XP_016883073.1
	XM_017027585.1			XP_016883074.1
	AK289866.1
	AK313517.1
	BC025286.1			AAH25286.1
	BC075835.1			AAH75835.1
	BC131747.1
	BM010247.1
	BX537992.1			CAD97951.1
	DA463753.1
	DA761891.1
	DA967881.1
	Y10376.1			CAA71404.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv39e213	Chr.20:1580276 - 1618432 on Build GRCh38	Gain	SIRPB1
nsv585206	Chr.20:1405829 - 1733716 on Build GRCh38	Gain	SIRPB1 SIRPG NSFL1C SIRPD SIRPG-AS1 SIRPB2
dgv4238n100	Chr.20:1586796 - 1618496 on Build GRCh38	Loss	SIRPB1
nsv1057460	Chr.20:1598463 - 1618926 on Build GRCh38	Loss	SIRPB1
dgv4233n100	Chr.20:1579885 - 1618496 on Build GRCh38	Gain+Loss	SIRPB1
nsv828665	Chr.20:1570997 - 1620511 on Build GRCh38	Loss	SIRPB1
nsv184	Chr.20:1570746 - 1619001 on Build GRCh38	Deletion	SIRPB1
esv2722071	Chr.20:1565136 - 1694217 on Build GRCh38	Deletion	SIRPB1 SIRPG SIRPG-AS1
nsv833894	Chr.20:1538787 - 1772720 on Build GRCh38	Gain	SIRPB1 SIRPG SIRPD SIRPG-AS1
esv2760679	Chr.20:1569688 - 1618432 on Build GRCh38	Gain+Loss	SIRPB1
nsv3253	Chr.20:1566446 - 1623186 on Build GRCh38	Deletion	SIRPB1
nsv522008	Chr.20:1359746 - 1657932 on Build GRCh38	Gain	SIRPB1 FKBP1A-SDCBP2 SIRPG NSFL1C SIRPD SIRPG-AS1 MIR6869 SIRPB2 FKBP1A SDCBP2-AS1
nsv965842	Chr.20:1611446 - 1618611 on Build GRCh38	Duplication	SIRPB1
nsv510779	Chr.20:1528684 - 1633316 on Build GRCh38	Deletion	SIRPB1 SIRPG SIRPD
nsv952974	Chr.20:1613555 - 1625154 on Build GRCh38	Duplication	SIRPB1
esv2722074	Chr.20:1604818 - 1636346 on Build GRCh38	Deletion	SIRPB1 SIRPG SIRPG-AS1
esv2758777	Chr.20:1496135 - 1698610 on Build GRCh38	Gain+Loss	SIRPB1 SIRPG SIRPD SIRPG-AS1
dgv4230n100	Chr.20:1576532 - 1618926 on Build GRCh38	Gain	SIRPB1
esv33908	Chr.20:1610532 - 1618143 on Build GRCh38	Loss	SIRPB1
dgv4235n100	Chr.20:1580129 - 1618926 on Build GRCh38	Loss	SIRPB1
nsv965840	Chr.20:1570604 - 1620470 on Build GRCh38	Duplication	SIRPB1
esv3644985	Chr.20:1616143 - 1619498 on Build GRCh38	Loss	SIRPB1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

signal transduction
cell surface receptor signaling pathway
innate immune response

Function(s)

protein binding