Hs04067661_cn

• Gene Symbol: CBR3
• Assay Reference Genome Location: Chr.21:36138579 on build GRCh38
• Cytoband: 21q22.12

Target Gene Details

• Entrez Gene ID: 874
• Gene Name: carbonyl reductase 3
• Gene Aliases: HEL-S-25, SDR21C2, hCBR3
• Location: Chr.21:36134901-36146562 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBR3	NM_001236.3			NP_001227.1
	XM_011529772.2			XP_011528074.1
	AB004850.1
	AB004854.1			BAA33500.1
	AB041012.1			BAD74062.1
	AB124847.1			BAE45939.1
	AK223429.1			BAD97149.1
	BC002812.2			AAH02812.1
	CR541709.1			CAG46510.1
	FJ224313.1

Target Gene Details

• Entrez Gene ID: 100506428
• Gene Name: CBR3 antisense RNA 1
• Gene Aliases: PlncRNA-1, PlncRNA1
• Location: Chr.21:36131767-36156308 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBR3-AS1	NR_038892.1
	NR_038893.1
	AL542398.3
	BI836686.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2751927	Chr.21:36061467 - 36286211 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2 CBR1
esv33578	Chr.21:36116014 - 36447329 on Build GRCh38	Loss	CBR3-AS1 CHAF1B CBR3 LOC100133286 DOPEY2 MORC3
dgv813e214	Chr.21:36104817 - 36246729 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2
esv2751928	Chr.21:36104061 - 36250617 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2
nsv587469	Chr.21:36135447 - 36139329 on Build GRCh38	Loss	CBR3-AS1 CBR3
nsv587466	Chr.21:36122680 - 36180950 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC100133286 DOPEY2
dgv4427n100	Chr.21:36103179 - 36252203 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2
esv3575388	Chr.21:36109602 - 36247236 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2
nsv516175	Chr.21:36126057 - 36245332 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC100133286 DOPEY2
nsv587464	Chr.21:36078285 - 36300908 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2
esv2763686	Chr.21:36088564 - 36248238 on Build GRCh38	Gain+Loss	CBR3-AS1 CBR3 LOC105369306 LOC100133286 DOPEY2
nsv459249	Chr.21:36118357 - 36231355 on Build GRCh38	Gain	CBR3-AS1 CBR3 LOC100133286 DOPEY2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

phylloquinone catabolic process
cognition
oxidation-reduction process

Function(s)

3-keto sterol reductase activity
carbonyl reductase (NADPH) activity
NADPH binding