Hs04074408_cn

• Gene Symbol: WDR4
• Assay Reference Genome Location: Chr.21:42858904 on build GRCh38
• Cytoband: 21q22.3

Target Gene Details

• Entrez Gene ID: 10785
• Gene Name: WD repeat domain 4
• Gene Aliases: TRM82, TRMT82
• Location: Chr.21:42843075-42879865 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
WDR4	NM_001260474.1			NP_001247403.1
	NM_001260475.1			NP_001247404.1
	NM_001260476.1			NP_001247405.1
	NM_001260477.1			NP_001247406.1
	NM_018669.5			NP_061139.2
	NM_033661.4			NP_387510.1
	NR_048535.1
	XM_011529433.1			XP_011527735.1
	XM_017028262.1			XP_016883751.1
	XM_017028263.1			XP_016883752.1
	XM_017028264.1			XP_016883753.1
	AJ243912.1			CAB93144.1
	AJ243913.1			CAB93145.1
	AK056343.1
	AK292923.1
	AK298015.1
	AK315008.1
	BC001074.2			AAH01074.1
	BC006341.2			AAH06341.1
	BU541429.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv587657	Chr.21:42752699 - 43087910 on Build GRCh38	Gain	PDE9A NDUFV3 PKNOX1 LOC101928311 ERVH48-1 CBS MIR5692B WDR4
esv3584478	Chr.21:42827914 - 42993457 on Build GRCh38	Gain	NDUFV3 PKNOX1 ERVH48-1 MIR5692B WDR4
esv2666871	Chr.21:42615442 - 43467915 on Build GRCh38	Deletion	PDE9A FRGCA LINC00322 LINC00319 LOC101928284 LOC400870 TCONS_00029157 LINC00313 SIK1 NDUFV3 HSF2BP PKNOX1 LOC101928311 ERVH48-1 CRYAA CBS MIR5692B U2AF1 LOC101928255 WDR4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA processing factor, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

tRNA modification
tRNA methylation
RNA (guanine-N7)-methylation

Function(s)

protein binding
tRNA (guanine-N7-)-methyltransferase activity