Hs04095182_cn

• Gene Symbol: LZTR1
• Assay Reference Genome Location: Chr.22:20983539 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 8216
• Gene Name: leucine zipper like transcription regulator 1
• Gene Aliases: BTBD29, LZTR-1, NS10, SWNTS2
• Location: Chr.22:20982269-20999037 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LZTR1	NM_006767.3			NP_006758.2
	AK296347.1
	AK310747.1
	BC026214.1			AAH26214.2
	CT841521.1			CAJ86451.1
	D38496.1			BAA07508.1
	DA194822.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3893441	Chr.22:20733858 - 21135629 on Build GRCh38	Gain+Loss	P2RX6P THAP7-AS1 P2RX6 MIR649 BCRP2 THAP7 PI4KA CRKL AIFM3 SLC7A4 SERPIND1 TUBA3FP SNAP29 LZTR1 LRRC74B LOC101928891
nsv1065617	Chr.22:20705383 - 21111546 on Build GRCh38	Gain	P2RX6P THAP7-AS1 P2RX6 MIR649 BCRP2 THAP7 PI4KA CRKL AIFM3 SLC7A4 SERPIND1 TUBA3FP SNAP29 LZTR1 LRRC74B LOC101928891
dgv7994n54	Chr.22:20559470 - 21111491 on Build GRCh38	Gain	P2RX6P THAP7-AS1 POM121L4P P2RX6 MIR649 BCRP2 MED15 THAP7 PI4KA CRKL AIFM3 SLC7A4 SMPD4P1 SERPIND1 TUBA3FP SNAP29 LZTR1 TMEM191A LRRC74B LOC101928891
nsv834142	Chr.22:20979844 - 21170235 on Build GRCh38	Gain	P2RX6P SLC7A4 THAP7-AS1 P2RX6 TUBA3FP FAM230B MIR649 BCRP2 THAP7 LZTR1 AIFM3 LRRC74B
nsv471185	Chr.22:20977267 - 21033678 on Build GRCh38	Loss	SLC7A4 THAP7-AS1 P2RX6 TUBA3FP THAP7 LZTR1 AIFM3
nsv834141	Chr.22:20859455 - 21051952 on Build GRCh38	Loss	P2RX6P THAP7-AS1 P2RX6 MIR649 THAP7 CRKL AIFM3 SLC7A4 TUBA3FP SNAP29 LZTR1 LRRC74B LOC101928891
nsv828961	Chr.22:20980653 - 21023359 on Build GRCh38	Gain	THAP7-AS1 P2RX6 TUBA3FP THAP7 LZTR1 AIFM3
esv2763693	Chr.22:20581182 - 21111546 on Build GRCh38	Gain	P2RX6P THAP7-AS1 POM121L4P P2RX6 MIR649 BCRP2 MED15 THAP7 PI4KA CRKL AIFM3 SLC7A4 SMPD4P1 SERPIND1 TUBA3FP SNAP29 LZTR1 TMEM191A LRRC74B LOC101928891
esv3647304	Chr.22:20902577 - 21081487 on Build GRCh38	Loss	P2RX6P SLC7A4 THAP7-AS1 P2RX6 TUBA3FP MIR649 THAP7 LZTR1 CRKL AIFM3 LRRC74B LOC101928891
nsv588306	Chr.22:20963144 - 21111491 on Build GRCh38	Gain	P2RX6P SLC7A4 THAP7-AS1 P2RX6 TUBA3FP MIR649 BCRP2 THAP7 LZTR1 AIFM3 LRRC74B LOC101928891
nsv588305	Chr.22:20721841 - 21108064 on Build GRCh38	Loss	P2RX6P THAP7-AS1 P2RX6 MIR649 BCRP2 THAP7 PI4KA CRKL AIFM3 SLC7A4 SERPIND1 TUBA3FP SNAP29 LZTR1 LRRC74B LOC101928891
esv2678175	Chr.22:20691629 - 21284480 on Build GRCh38	Deletion	P2RX6P THAP7-AS1 POM121L4P P2RX6 FAM230B MIR649 BCRP2 THAP7 PI4KA CRKL AIFM3 SLC7A4 SERPIND1 TUBA3FP POM121L8P SNAP29 GGT2 LZTR1 TMEM191A LRRC74B LOC101928891
dgv7993n54	Chr.22:20346736 - 21111491 on Build GRCh38	Gain	BCRP2 THAP7 SCARF2 SLC7A4 SMPD4P1 SERPIND1 SNAP29 ZNF74 LOC101928891 P2RX6P THAP7-AS1 POM121L4P P2RX6 LOC101927859 MIR649 MED15 KLHL22 PI4KA CRKL AIFM3 USP41 TUBA3FP LZTR1 TMEM191A LRRC74B
dgv4483n100	Chr.22:20362634 - 21212930 on Build GRCh38	Gain	FAM230B BCRP2 THAP7 SCARF2 SLC7A4 SMPD4P1 SERPIND1 SNAP29 ZNF74 LOC101928891 P2RX6P THAP7-AS1 POM121L4P P2RX6 MIR649 MED15 KLHL22 PI4KA CRKL AIFM3 USP41 TUBA3FP GGT2 LZTR1 TMEM191A LRRC74B
nsv523162	Chr.22:20389246 - 21108064 on Build GRCh38	Loss	P2RX6P THAP7-AS1 POM121L4P P2RX6 MIR649 BCRP2 MED15 KLHL22 THAP7 PI4KA CRKL AIFM3 SCARF2 SLC7A4 USP41 SMPD4P1 SERPIND1 TUBA3FP SNAP29 ZNF74 LZTR1 TMEM191A LRRC74B LOC101928891
nsv828960	Chr.22:20953775 - 21057148 on Build GRCh38	Loss	P2RX6P SLC7A4 THAP7-AS1 P2RX6 TUBA3FP MIR649 THAP7 LZTR1 AIFM3 LRRC74B LOC101928891

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated
anatomical structure morphogenesis

Function(s)

transcription factor activity, sequence-specific DNA binding