Hs04104484_cn

• Gene Symbol: AR
• Assay Reference Genome Location: Chr.X:67565118 on build GRCh38
• Cytoband: Xq12

Target Gene Details

• Entrez Gene ID: 367
• Gene Name: androgen receptor
• Gene Aliases: AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
• Location: Chr.X:67544032-67730619 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AR	NM_000044.3			NP_000035.2
	AF162704.1			AAD45921.1
	BC132975.1
	FJ235916.1
	FJ235917.1
	FJ235918.1
	FJ235919.1
	FJ235920.1
	GU208210.1
	HM055487.1
	KJ534771.1
	L29496.1			AAA51770.1
	M20132.1			AAA51729.1
	M20260.1			AAA51774.1
	M21748.1			AAA51771.1
	M23263.1			AAA51775.1
	M34233.1			AAA51780.1
	M73069.1			AAA51735.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2758871	Chr.X:67279827 - 68099252 on Build GRCh38	Gain	OPHN1 AR
nsv818030	Chr.X:67496364 - 68089458 on Build GRCh38	Gain	OPHN1 AR

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
transport
signal transduction
cell-cell signaling
sex differentiation
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of gene expression
cell growth
androgen receptor signaling pathway
intracellular receptor signaling pathway
prostate gland development
positive regulation of phosphorylation
positive regulation of cell differentiation
negative regulation of integrin biosynthetic process
positive regulation of integrin biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase III promoter
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
regulation of establishment of protein localization to plasma membrane
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
androgen receptor activity
receptor binding
steroid binding
androgen binding
protein binding
beta-catenin binding
transcription factor binding
zinc ion binding
enzyme binding
transcription regulatory region DNA binding
protein dimerization activity
ATPase binding