Hs04258789_cn

• Gene Symbol: SRPRB
• Assay Reference Genome Location: Chr.3:133784900 on build GRCh38
• Cytoband: 3q22.1

Target Gene Details

• Entrez Gene ID: 58477
• Gene Name: SRP receptor beta subunit
• Gene Aliases: APMCF1
• Location: Chr.3:133784033-133821492 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SRPRB	NM_021203.3			NP_067026.3
	DB448771.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv513074	Chr.3:133784364 - 133786594 on Build GRCh38	Loss	SRPRB
esv3562578	Chr.3:133784643 - 133786493 on Build GRCh38	Deletion	SRPRB
esv2725943	Chr.3:133784896 - 133786242 on Build GRCh38	Deletion	SRPRB
nsv965212	Chr.3:133784891 - 133787472 on Build GRCh38	Duplication	SRPRB
nsv829729	Chr.3:133726027 - 133901543 on Build GRCh38	Loss	RAB6B TF SRPRB
nsv4018	Chr.3:133767023 - 133811824 on Build GRCh38	Deletion	TF SRPRB
esv989994	Chr.3:133784924 - 133786239 on Build GRCh38	Deletion	SRPRB
esv8734	Chr.3:133784706 - 133786378 on Build GRCh38	Loss	SRPRB
esv3892	Chr.3:133784814 - 133786372 on Build GRCh38	Loss	SRPRB
esv1005045	Chr.3:133782747 - 133792129 on Build GRCh38	Deletion	SRPRB
dgv1408e212	Chr.3:133780590 - 133789415 on Build GRCh38	Loss	SRPRB
esv2661320	Chr.3:133784922 - 133786238 on Build GRCh38	Deletion	SRPRB
esv1301210	Chr.3:133784938 - 133786254 on Build GRCh38	Deletion	SRPRB
esv2833792	Chr.3:133784927 - 133786243 on Build GRCh38	Deletion	SRPRB

More Information

Additional Information:

For this assay, SNP(s) [rs538344066,rs569107793] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

SRP-dependent cotranslational protein targeting to membrane
small GTPase mediated signal transduction
IRE1-mediated unfolded protein response

Function(s)

signal recognition particle binding
GTP binding