Hs04300375_cn

• Gene Symbol: NR3C1
• Assay Reference Genome Location: Chr.5:143292983 on build GRCh38
• Cytoband: 5q31.3

Target Gene Details

• Entrez Gene ID: 2908
• Gene Name: nuclear receptor subfamily 3 group C member 1
• Gene Aliases: GCCR, GCR, GCRST, GR, GRL
• Location: Chr.5:143277931-143435512 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NR3C1	NM_000176.2			NP_000167.1
	NM_001018074.1			NP_001018084.1
	NM_001018075.1			NP_001018085.1
	NM_001018076.1			NP_001018086.1
	NM_001018077.1			NP_001018087.1
	NM_001020825.1			NP_001018661.1
	NM_001024094.1			NP_001019265.1
	NM_001204258.1			NP_001191187.1
	NM_001204259.1			NP_001191188.1
	NM_001204260.1			NP_001191189.1
	NM_001204261.1			NP_001191190.1
	NM_001204262.1			NP_001191191.1
	NM_001204263.1			NP_001191192.1
	NM_001204264.1			NP_001191193.1
	XM_005268419.3			XP_005268476.1
	XM_005268420.4			XP_005268477.1
	XM_005268422.3			XP_005268479.1
	XM_005268423.3			XP_005268480.1
	XM_011537637.2			XP_011535939.1
	XM_017009397.1			XP_016864886.1
	XM_017009398.1			XP_016864887.1
	AB307716.1
	AK223594.1			BAD97314.1
	AK302050.1
	AK314789.1
	AM183262.1
	BC015610.2			AAH15610.1
	BX640610.1			CAE45716.1
	BX648553.1
	HQ450643.1
	HQ450644.1
	HQ692822.1
	JN797823.1
	JN797824.1
	U01351.1			AAA16603.1
	X03225.1			CAA26976.1
	X03348.1			CAA27054.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv5041	Chr.5:143273624 - 143318331 on Build GRCh38	Deletion	NR3C1
nsv950421	Chr.5:143289236 - 143402835 on Build GRCh38	Duplication	NR3C1
esv33748	Chr.5:143258702 - 143320030 on Build GRCh38	Loss	NR3C1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
apoptotic process
chromosome segregation
mitotic nuclear division
signal transduction
covalent chromatin modification
glucocorticoid receptor signaling pathway
glucocorticoid mediated signaling pathway
positive regulation of transcription from RNA polymerase II promoter
cell division
cellular response to steroid hormone stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA binding
glucocorticoid receptor activity
steroid binding
protein binding
zinc ion binding
protein complex binding
glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity
steroid hormone binding