Hs04347147_cn

• Gene Symbol: SGK223
• Assay Reference Genome Location: Chr.8:8344701 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 157285
• Gene Name: homolog of rat pragma of Rnd2
• Gene Aliases: PRAGMIN
• Location: Chr.8:8317731-8386444 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SGK223	NM_001080826.2			NP_001074295.2
	XM_005272369.4			XP_005272426.2
	XM_005272370.4			XP_005272427.2
	XM_011543813.2			XP_011542115.1
	AK122582.1			BAC56923.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv610154	Chr.8:8244119 - 8470591 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2764098	Chr.8:7102311 - 8743201 on Build GRCh38	Gain+Loss	FAM66B USP17L3 DEFB109P1B SPAG11B DEFB103B USP17L8 FAM90A7P FAM86B3P DEFB105A DEFB107A LOC101928095 DEFB4B PRR23D2 DEFB103A DEFB104A MIR548I3 FAM90A10P PRR23D1 ZNF705B DEFB106A LOC101929400 FAM66E USP17L4 USP17L1 LOC107986910 DEFB4A SPAG11A CLDN23 DEFB108P1 OR7E125P DEFB104B SGK223 OR7E154P LINC00965 ZNF705G DEFB106B DEFB105B DEFB107B
nsv610153	Chr.8:8240557 - 8597021 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2759589	Chr.8:6874198 - 8449233 on Build GRCh38	Gain+Loss	FAM66B USP17L3 DEFB109P1B SPAG11B DEFB103B USP17L8 FAM90A7P FAM86B3P DEFA11P DEFB105A LOC101928095 DEFA10P PRR23D2 DEFB103A DEFB104A MIR548I3 FAM90A10P PRR23D1 DEFB106A FAM66E USP17L4 USP17L1 LOC107986910 SPAG11A OR7E125P SGK223 OR7E154P DEFT1P LINC00965 DEFA1 DEFB105B DEFB107A DEFB4B ZNF705B DEFA4 LOC101929400 DEFT1P2 DEFB1 DEFA6 DEFA9P DEFA1B DEFB4A DEFB108P1 DEFB104B DEFA7P ZNF705G DEFA3 DEFB106B DEFB107B DEFA8P DEFA5
nsv610156	Chr.8:8305721 - 8349823 on Build GRCh38	Loss	SGK223

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine phosphorylation

Function(s)

protein kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding