Hs04349136_cn

• Gene Symbol: SGK223
• Assay Reference Genome Location: Chr.8:8346529 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 157285
• Gene Name: homolog of rat pragma of Rnd2
• Gene Aliases: PRAGMIN
• Location: Chr.8:8317731-8386444 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SGK223	NM_001080826.2			NP_001074295.2
	XM_005272369.4			XP_005272426.2
	XM_005272370.4			XP_005272427.2
	XM_011543813.2			XP_011542115.1
	AK122582.1			BAC56923.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv610154	Chr.8:8244119 - 8470591 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2764098	Chr.8:7102311 - 8743201 on Build GRCh38	Gain+Loss	ZNF705B SPAG11A LOC107986910 USP17L8 OR7E125P SGK223 DEFB104B DEFB106A USP17L1 DEFB4B FAM66B USP17L4 FAM66E PRR23D1 DEFB108P1 PRR23D2 ZNF705G DEFB105A DEFB109P1B FAM90A7P DEFB4A USP17L3 DEFB105B FAM90A10P DEFB103A DEFB106B DEFB107A DEFB103B OR7E154P DEFB104A LOC101928095 CLDN23 SPAG11B DEFB107B LINC00965 MIR548I3 LOC101929400 FAM86B3P
nsv610153	Chr.8:8240557 - 8597021 on Build GRCh38	Loss	SGK223 FAM86B3P
esv2759589	Chr.8:6874198 - 8449233 on Build GRCh38	Gain+Loss	DEFT1P LOC107986910 DEFB4B FAM66B USP17L4 DEFA10P DEFA9P DEFA7P DEFT1P2 DEFB109P1B USP17L3 FAM90A10P DEFB103A DEFB106B OR7E154P DEFB104A DEFA1B LOC101928095 SPAG11B DEFB107B MIR548I3 FAM86B3P ZNF705B SPAG11A USP17L8 OR7E125P SGK223 DEFB104B DEFB106A USP17L1 FAM66E PRR23D1 DEFB108P1 PRR23D2 DEFA5 ZNF705G DEFA8P DEFB105A DEFA3 FAM90A7P DEFB4A DEFB105B DEFA11P DEFA1 DEFB107A DEFB103B DEFB1 DEFA4 LINC00965 DEFA6 LOC101929400
nsv610156	Chr.8:8305721 - 8349823 on Build GRCh38	Loss	SGK223

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine phosphorylation

Function(s)

protein kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding