Hs04375277_cn

• Gene Symbol: KNDC1
• Assay Reference Genome Location: Chr.10:133170471 on build GRCh38
• Cytoband: 10q26.3

Target Gene Details

• Entrez Gene ID: 85442
• Gene Name: kinase non-catalytic C-lobe domain containing 1
• Gene Aliases: C10orf23, RASGEF2, bB439H18.3
• Location: Chr.10:133160096-133226412 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KNDC1	NM_152643.6			NP_689856.6
	XM_017016858.1			XP_016872347.1
	XM_017016859.1			XP_016872348.1
	AB000781.1			BAD12625.1
	AB051555.1			BAB21859.1
	AI146357.1
	AI951527.1
	AK090457.1			BAC03438.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759793	Chr.10:133030918 - 133619181 on Build GRCh38	Gain+Loss	ZNF511 KNDC1 VENTX SYCE1 CALY ADGRA1-AS1 TUBGCP2 ADAM8 MIR202HG PRAP1 ECHS1 MTG1 FUOM UTF1 CYP2E1 SCART1 PAOX MIR202 SPRN ADGRA1 MIR3944 SPRNP1
dgv998n100	Chr.10:132998894 - 133170978 on Build GRCh38	Gain	KNDC1 ADGRA1-AS1 ADGRA1
nsv1159784	Chr.10:133132423 - 133263092 on Build GRCh38	Deletion	MIR202HG UTF1 KNDC1 VENTX MIR202 ADAM8
esv2760107	Chr.10:133121116 - 133286029 on Build GRCh38	Gain	MIR202HG UTF1 KNDC1 VENTX MIR202 ADGRA1 TUBGCP2 ADAM8
nsv7630	Chr.10:133133994 - 133170839 on Build GRCh38	Deletion	KNDC1
dgv1465n54	Chr.10:133107631 - 133189333 on Build GRCh38	Loss	KNDC1 ADGRA1
nsv832038	Chr.10:133143596 - 133320747 on Build GRCh38	Gain+Loss	MIR202HG ZNF511 UTF1 KNDC1 VENTX MIR202 TUBGCP2 ADAM8
nsv528260	Chr.10:132859348 - 133620799 on Build GRCh38	Loss	KNDC1 LINC01167 LINC01168 SYCE1 ADGRA1-AS1 ADAM8 MTG1 FUOM UTF1 CYP2E1 PAOX MIR202 ADGRA1 LINC01166 MIR3944 ZNF511 VENTX CALY TUBGCP2 MIR202HG PRAP1 ECHS1 SCART1 SPRN SPRNP1 CFAP46
nsv832036	Chr.10:133089509 - 133368232 on Build GRCh38	Loss	ZNF511 KNDC1 VENTX CALY TUBGCP2 ADAM8 MIR202HG PRAP1 ECHS1 FUOM UTF1 MIR202 ADGRA1
nsv552574	Chr.10:133140872 - 133249523 on Build GRCh38	Gain	MIR202HG UTF1 KNDC1 VENTX MIR202
nsv832039	Chr.10:133161709 - 133267664 on Build GRCh38	Loss	MIR202HG UTF1 KNDC1 VENTX MIR202 ADAM8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
small GTPase mediated signal transduction
biological_process
cerebellar granule cell differentiation
positive regulation of GTPase activity
regulation of dendrite morphogenesis

Function(s)

molecular_function
Ras guanyl-nucleotide exchange factor activity