Hs04416067_cn

• Gene Symbol: KLRB1
• Assay Reference Genome Location: Chr.12:9607138 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 3820
• Gene Name: killer cell lectin like receptor B1
• Gene Aliases: CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
• Location: Chr.12:9595274-9607901 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRB1	NM_002258.2			NP_002249.1
	AK292022.1
	BC113997.1			AAI13998.1
	BC114516.1			AAI14517.1
	BF432813.1
	U11276.1			AAA21605.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	AICDA LINC00612 LOC105369649 LOC101928030 OVOS CLEC4D CLEC2B LOC101930452 MIR1244-3 LINC00987 LOC642846 CLEC2A A2MP1 CLEC4E CLECL1 CLEC6A A2ML1 DDX12P M6PR LOC105369728 A2M KLRB1 PHC1 A2M-AS1 MFAP5 PZP CLEC2D LOC400002 KLRF1 LOC100506159 LOC105376678 LOC728715 CLEC12A KLRG1 LOC374443 RIMKLB KLRF2 CD69
esv3628509	Chr.12:9603613 - 9613864 on Build GRCh38	Loss	KLRB1
nsv603	Chr.12:9605313 - 9637467 on Build GRCh38	Insertion	KLRB1 LOC374443
esv3628510	Chr.12:9604249 - 9611309 on Build GRCh38	Loss	KLRB1
esv2759878	Chr.12:9218999 - 9770933 on Build GRCh38	Gain+Loss	DDX12P LOC105369728 LOC105369649 KLRB1 LOC101928030 OVOS LOC101930452 CLEC2D LOC105376678 MIR1244-3 LOC728715 LINC00987 LOC642846 KLRG1 A2MP1 LOC374443 CLECL1 CD69
nsv428271	Chr.12:9407491 - 9678072 on Build GRCh38	Gain	DDX12P LOC105376678 LOC105369728 KLRB1 OVOS LOC374443 CLEC2D

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

cell surface receptor signaling pathway
regulation of immune response

Function(s)

transmembrane signaling receptor activity
carbohydrate binding