Hs04448133_cn

• Gene Symbol: ADAMTS7
• Assay Reference Genome Location: Chr.15:78767688 on build GRCh38
• Cytoband: 15q25.1

Target Gene Details

• Entrez Gene ID: 11173
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 7
• Gene Aliases: ADAM-TS 7, ADAM-TS7, ADAMTS-7
• Location: Chr.15:78759203-78811464 on Build GRCh38
• Assay Gene Location: Within Intron 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAMTS7	NM_014272.4			NP_055087.2
	XM_005254137.3			XP_005254194.1
	XM_011521166.2			XP_011519468.1
	AK299844.1
	AL110226.1			CAB53684.1
	AY327122.1
	BC061631.1			AAH61631.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952004	Chr.15:78730159 - 78800258 on Build GRCh38	Deletion	ADAMTS7 LOC646938
esv33573	Chr.15:78761142 - 79001539 on Build GRCh38	Gain+Loss	ADAMTS7 RASGRF1 CTSH MORF4L1

More Information

Additional Information:

For this assay, SNP(s) [rs148106161] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

negative regulation of chondrocyte differentiation
protein O-linked fucosylation
proteolysis involved in cellular protein catabolic process
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to BMP stimulus
mitophagy in response to mitochondrial depolarization

Function(s)

metalloendopeptidase activity
protein binding
metallopeptidase activity
zinc ion binding