Hs04559639_cn

• Gene Symbol: GLS
• Assay Reference Genome Location: Chr.2:190891318 on build GRCh38
• Cytoband: 2q32.2

Target Gene Details

• Entrez Gene ID: 2744
• Gene Name: glutaminase
• Gene Aliases: AAD20, GAC, GAM, GLS1, KGA
• Location: Chr.2:190880821-190965552 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLS	NM_001256310.1			NP_001243239.1
	NM_014905.4			NP_055720.3
	XM_005246467.3			XP_005246524.1
	XM_006712435.1			XP_006712498.1
	XM_017003829.1			XP_016859318.1
	AB020645.1
	AF097492.1			AAF00088.1
	AF097495.1			AAF00090.1
	AF158555.1			AAD47056.1
	AF223943.1			AAF33825.1
	AF327434.1			AAG47842.1
	AK289747.1
	BC038507.1			AAH38507.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv999391	Chr.2:190884309 - 191057205 on Build GRCh38	Gain	LOC105373805 STAT1 STAT4 GLS
nsv3083	Chr.2:190880106 - 190914039 on Build GRCh38	Insertion	GLS
nsv584065	Chr.2:190779811 - 191011175 on Build GRCh38	Loss	STAT1 GLS

More Information

Additional Information:

For this assay, SNP(s) [rs114000177] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

hydrolase

Gene Ontology Categories:

Process(es)

suckling behavior
regulation of respiratory gaseous exchange by neurological system process
glutamate biosynthetic process
glutamine catabolic process
chemical synaptic transmission
cellular amino acid biosynthetic process
glutamate secretion
protein homotetramerization

Function(s)

glutaminase activity
protein binding