Hs04588949_cn

• Gene Symbol: IL1R1
• Assay Reference Genome Location: Chr.2:102081479 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 3554
• Gene Name: interleukin 1 receptor type 1
• Gene Aliases: CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
• Location: Chr.2:102069638-102179874 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL1R1	NM_001288706.1			NP_001275635.1
	NM_001320978.1			NP_001307907.1
	XM_011511115.2			XP_011509417.1
	XM_011511117.1			XP_011509419.1
	AK314433.1
	DA861783.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518990	Chr.2:102074850 - 102094571 on Build GRCh38	Gain	IL1R1
nsv2852	Chr.2:102062195 - 102100116 on Build GRCh38	Deletion	IL1R1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

immune response
cell surface receptor signaling pathway
response to radiation
heat acclimation
ovulation
regulation of inflammatory response
interleukin-1-mediated signaling pathway
response to interleukin-1
response to epidermal growth factor
cellular response to glucose stimulus
response to transforming growth factor beta
response to nitric oxide

Function(s)

protease binding
signal transducer activity
transmembrane signaling receptor activity
interleukin-1 receptor activity
interleukin-1, Type I, activating receptor activity
platelet-derived growth factor receptor binding
protein binding
ionotropic glutamate receptor binding