Hs04619248_cn

• Gene Symbol: ABI2
• Assay Reference Genome Location: Chr.2:203335071 on build GRCh38
• Cytoband: 2q33.2

Target Gene Details

• Entrez Gene ID: 10152
• Gene Name: abl-interactor 2
• Gene Aliases: ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBP1, argBPIA, argBPIB
• Location: Chr.2:203327874-203432173 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ABI2	NM_001282925.1			NP_001269854.1
	NM_001282926.1			NP_001269855.1
	NM_001282932.1			NP_001269861.1
	NM_005759.5			NP_005750.4
	XM_005246217.2			XP_005246274.1
	XM_005246218.2			XP_005246275.1
	XM_005246221.2			XP_005246278.1
	XM_005246225.2			XP_005246282.1
	XM_005246226.2			XP_005246283.1
	XM_006712174.2			XP_006712237.1
	XM_006712177.2			XP_006712240.1
	XM_006712179.2			XP_006712242.1
	XM_006712180.2			XP_006712243.1
	XM_006712181.2			XP_006712244.1
	XM_006712182.2			XP_006712245.1
	XM_006712185.1			XP_006712248.1
	XM_006712186.2			XP_006712249.1
	XM_011510472.2			XP_011508774.1
	XM_017003118.1			XP_016858607.1
	XM_017003119.1			XP_016858608.1
	XM_017003120.1			XP_016858609.1
	XM_017003121.1			XP_016858610.1
	XM_017003122.1			XP_016858611.1
	XM_017003123.1			XP_016858612.1
	XM_017003124.1			XP_016858613.1
	XM_017003125.1			XP_016858614.1
	XM_017003126.1			XP_016858615.1
	XM_017003127.1			XP_016858616.1
	XM_017003128.1			XP_016858617.1
	XM_017003129.1			XP_016858618.1
	XM_017003130.1			XP_016858619.1
	XM_017003131.1			XP_016858620.1
	XM_017003132.1			XP_016858621.1
	XM_017003133.1			XP_016858622.1
	XM_017003134.1			XP_016858623.1
	XM_017003135.1			XP_016858624.1
	XM_017003136.1			XP_016858625.1
	XM_017003137.1			XP_016858626.1
	XM_017003138.1			XP_016858627.1
	XM_017003139.1			XP_016858628.1
	XM_017003140.1			XP_016858629.1
	XM_017003141.1			XP_016858630.1
	XM_017003142.1			XP_016858631.1
	XM_017003143.1			XP_016858632.1
	XM_017003144.1			XP_016858633.1
	XM_017003145.1			XP_016858634.1
	XM_017003146.1			XP_016858635.1
	AF260261.1			AAF70308.1
	AK294429.1
	AK299824.1
	AK302853.1
	AK311427.1
	AK316000.1
	BC001439.2			AAH01439.1
	BT009920.1			AAP88922.1
	DB455742.1
	DC376086.1
	X95632.1			CAA64885.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1001799	Chr.2:202908732 - 205615330 on Build GRCh38	Gain	PARD3B WDR12 CD28 RAPH1 ICOS ABI2 CARF NBEAL1 RPL12P16 CTLA4 CYP20A1
nsv3115	Chr.2:203315491 - 203357486 on Build GRCh38	Deletion	ABI2

More Information

Additional Information:

For this assay, SNP(s) [rs77976487] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

movement of cell or subcellular component
cytoskeleton organization
actin polymerization or depolymerization
viral process
cell migration
Rac protein signal transduction
peptidyl-tyrosine phosphorylation
positive regulation of Arp2/3 complex-mediated actin nucleation

Function(s)

DNA binding
protein binding
cytoskeletal adaptor activity
SH3 domain binding
kinase binding
ubiquitin protein ligase binding
protein complex binding
Rac GTPase binding
proline-rich region binding