Hs04620185_cn

• Gene Symbol: THNSL2
• Assay Reference Genome Location: Chr.2:88180701 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 55258
• Gene Name: threonine synthase like 2
• Gene Aliases: SOFAT, THS2, TSH2
• Location: Chr.2:88170295-88186637 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
THNSL2	NM_001244676.1			NP_001231605.1
	NM_001244678.1			NP_001231607.1
	NM_018271.4			NP_060741.3
	XM_005264400.4			XP_005264457.1
	XM_005264401.4			XP_005264458.1
	XM_005264402.3			XP_005264459.1
	XM_005264403.4			XP_005264460.1
	XM_005264405.4			XP_005264462.1
	XM_006712041.3			XP_006712104.1
	XM_006712042.3			XP_006712105.1
	XM_006712043.2			XP_006712106.1
	XM_006712044.3			XP_006712107.1
	XM_011532953.2			XP_011531255.1
	XM_011532954.2			XP_011531256.1
	XM_011532955.2			XP_011531257.1
	AK001778.1			BAA91904.1
	AK095303.1
	AK289486.1
	AK315831.1
	AL832746.1
	BC035315.1			AAH35315.1
	BC047758.2			AAH47758.2
	BC064423.1			AAH64423.1
	HM185274.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv61n16	Chr.2:87343737 - 90254660 on Build GRCh38	Deletion	TEX37 SMYD1 MIR4780 IGKV3-20 THNSL2 MIR4435-1 IGKV1D-8 MIR4436A IGKV2-29 IGKV1-5 LOC101927050 LOC101928403 PLGLB2 LINC00152 KRCC1 RGPD2 LOC730268 LOC107985911 IGKV2-24 IGKC IGKV2-26 IGKV3D-15 EIF2AK3 FOXI3 IGKV1D-13 ANKRD36BP2 RPIA LOC101928371 IGK FABP1
dgv6947n54	Chr.2:87815738 - 88850700 on Build GRCh38	Gain	TEX37 SMYD1 MIR4780 EIF2AK3 THNSL2 FOXI3 MIR4436A ANKRD36BP2 RPIA LOC101928403 LOC101928371 KRCC1 RGPD2 FABP1
nsv1072005	Chr.2:87360367 - 90256528 on Build GRCh38	Deletion	TEX37 SMYD1 MIR4780 IGKV3-20 THNSL2 MIR4435-1 IGKV1D-8 MIR4436A IGKV2-29 IGKV1-5 LOC101927050 LOC101928403 PLGLB2 LINC00152 KRCC1 RGPD2 LOC730268 LOC107985911 IGKV2-24 IGKC IGKV2-26 IGKV3D-15 EIF2AK3 FOXI3 IGKV1D-13 ANKRD36BP2 RPIA LOC101928371 IGK FABP1
nsv834289	Chr.2:88083076 - 88251327 on Build GRCh38	Gain	SMYD1 THNSL2 FABP1
nsv1130752	Chr.2:87360364 - 90256525 on Build GRCh38	Deletion	TEX37 SMYD1 MIR4780 IGKV3-20 THNSL2 MIR4435-1 IGKV1D-8 MIR4436A IGKV2-29 IGKV1-5 LOC101927050 LOC101928403 PLGLB2 LINC00152 KRCC1 RGPD2 LOC730268 LOC107985911 IGKV2-24 IGKC IGKV2-26 IGKV3D-15 EIF2AK3 FOXI3 IGKV1D-13 ANKRD36BP2 RPIA LOC101928371 IGK FABP1
nsv582384	Chr.2:87987149 - 88773214 on Build GRCh38	Loss	TEX37 SMYD1 MIR4780 EIF2AK3 THNSL2 FOXI3 ANKRD36BP2 RPIA LOC101928403 LOC101928371 KRCC1 RGPD2 FABP1
nsv582386	Chr.2:88035188 - 89208087 on Build GRCh38	Loss	TEX37 IGKV2-24 SMYD1 MIR4780 IGKV3-20 IGKC IGKV2-26 EIF2AK3 THNSL2 FOXI3 MIR4436A ANKRD36BP2 IGKV1-5 RPIA LOC101928403 LOC101928371 KRCC1 IGK FABP1
nsv582383	Chr.2:87915816 - 88527080 on Build GRCh38	Gain	TEX37 SMYD1 MIR4780 KRCC1 RGPD2 THNSL2 FABP1 FOXI3

More Information

Additional Information:

For this assay, SNP(s) [rs73949230] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

biological_process
serine family amino acid catabolic process
threonine biosynthetic process
dephosphorylation
2-oxobutyrate biosynthetic process

Function(s)

molecular_function
threonine synthase activity
cytokine activity
pyridoxal phosphate binding
serine binding