Hs04671569_cn

• Gene Symbol: PSMD14
• Assay Reference Genome Location: Chr.2:161310407 on build GRCh38
• Cytoband: 2q24.2

Target Gene Details

• Entrez Gene ID: 10213
• Gene Name: proteasome 26S subunit, non-ATPase 14
• Gene Aliases: PAD1, POH1, RPN11
• Location: Chr.2:161308275-161411717 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PSMD14	NM_005805.5			NP_005796.1
	AK055128.1
	BC066336.1			AAH66336.1
	DA133201.1
	U86782.1			AAC51866.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv583500	Chr.2:161203306 - 161389321 on Build GRCh38	Loss	TANK PSMD14 LOC101929512 LOC100996579

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
double-strand break repair via homologous recombination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
double-strand break repair via nonhomologous end joining
ubiquitin-dependent protein catabolic process
regulation of cellular amino acid metabolic process
positive regulation of endopeptidase activity
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
response to ethanol
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
regulation of proteasomal protein catabolic process
protein K63-linked deubiquitination
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway

Function(s)

protein binding
metallopeptidase activity
metal ion binding
endopeptidase activator activity
proteasome binding