Hs04718420_cn

• Gene Symbol: LMLN
• Assay Reference Genome Location: Chr.3:197975229 on build GRCh38
• Cytoband: 3q29

Target Gene Details

• Entrez Gene ID: 89782
• Gene Name: leishmanolysin like peptidase
• Gene Aliases: GP63, INV, IX14, MSP
• Location: Chr.3:197960200-198043720 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LMLN	NM_001136049.2			NP_001129521.2
	NM_033029.3			NP_149018.2
	NR_026786.1
	NR_026787.1
	XM_011513270.1			XP_011511572.1
	XM_011513271.1			XP_011511573.1
	XM_017007428.1			XP_016862917.1
	AJ312398.1			CAC42882.1
	AJ312399.1			CAC42883.1
	AK299119.1
	AL832783.1
	AM920777.1
	AM920778.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3599331	Chr.3:197953544 - 197984148 on Build GRCh38	Gain	IQCG RPL35A LMLN
esv2763718	Chr.3:197746211 - 198169247 on Build GRCh38	Gain+Loss	FAM157A RUBCN IQCG RPL35A LMLN-AS1 ANKRD18DP LRCH3 LMLN FYTTD1
dgv5045n100	Chr.3:197843263 - 198129562 on Build GRCh38	Gain	IQCG RPL35A LMLN-AS1 ANKRD18DP LRCH3 LMLN
nsv1013844	Chr.3:197902008 - 197975418 on Build GRCh38	Gain	IQCG RPL35A LMLN
nsv527527	Chr.3:197842688 - 198087104 on Build GRCh38	Gain	IQCG RPL35A LMLN-AS1 ANKRD18DP LRCH3 LMLN
esv2751989	Chr.3:197748569 - 198106887 on Build GRCh38	Gain	RUBCN IQCG RPL35A LMLN-AS1 ANKRD18DP LRCH3 LMLN FYTTD1
esv3893855	Chr.3:197912510 - 198111391 on Build GRCh38	Gain	IQCG RPL35A LMLN-AS1 ANKRD18DP LMLN
nsv1009299	Chr.3:197916770 - 198018555 on Build GRCh38	Gain	IQCG RPL35A LMLN
nsv999711	Chr.3:197871402 - 198011040 on Build GRCh38	Gain	IQCG RPL35A LRCH3 LMLN
esv3599324	Chr.3:197837661 - 197996085 on Build GRCh38	Gain	IQCG RPL35A LRCH3 LMLN
dgv5044n100	Chr.3:197821762 - 197975418 on Build GRCh38	Gain	IQCG RPL35A LRCH3 LMLN

More Information

Additional Information:

For this assay, SNP(s) [rs77259890] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease, protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

proteolysis
mitotic nuclear division
cell adhesion
cell division

Function(s)

metalloendopeptidase activity
metal ion binding