Hs04749150_cn

• Gene Symbol: SIAH2
• Assay Reference Genome Location: Chr.3:150758317 on build GRCh38
• Cytoband: 3q25.1

Target Gene Details

• Entrez Gene ID: 6478
• Gene Name: siah E3 ubiquitin protein ligase 2
• Gene Aliases: hSiah2
• Location: Chr.3:150741123-150763476 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIAH2	NM_005067.5			NP_005058.3
	AK223565.1			BAD97285.1
	BC013082.2			AAH13082.1
	U76248.1			AAC51908.1
	Y15268.1			CAA75557.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein polyubiquitination
ubiquitin-dependent protein catabolic process
apoptotic process
cell cycle
small GTPase mediated signal transduction
axon guidance
regulation of protein ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cellular protein catabolic process
cellular protein metabolic process
negative regulation of canonical Wnt signaling pathway
negative regulation of nucleic acid-templated transcription
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

transcription corepressor activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin conjugating enzyme binding
ubiquitin protein ligase activity