Hs04763644_cn

• Gene Symbol: MAP3K13
• Assay Reference Genome Location: Chr.3:185308310 on build GRCh38
• Cytoband: 3q27.2

Target Gene Details

• Entrez Gene ID: 9175
• Gene Name: mitogen-activated protein kinase kinase kinase 13
• Gene Aliases: LZK, MEKK13, MLK
• Location: Chr.3:185282938-185489094 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP3K13	NM_001242314.1			NP_001229243.1
	NM_001242317.1			NP_001229246.1
	XM_017007456.1			XP_016862945.1
	XM_017007458.1			XP_016862947.1
	AK297646.1
	AK312714.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829817	Chr.3:185227125 - 185409387 on Build GRCh38	Gain	EHHADH MIR5588 MAP3K13
esv3893837	Chr.3:185291669 - 185483550 on Build GRCh38	Gain	TMEM41A MAP3K13
esv3598966	Chr.3:185273685 - 185354155 on Build GRCh38	Gain	EHHADH MAP3K13

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
protein phosphorylation
JNK cascade
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity

Function(s)

protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
identical protein binding
protein homodimerization activity
metal ion binding