Hs04845316_cn

• Gene Symbol: METAP1
• Assay Reference Genome Location: Chr.4:99034057 on build GRCh38
• Cytoband: 4q23

Target Gene Details

• Entrez Gene ID: 23173
• Gene Name: methionyl aminopeptidase 1
• Gene Aliases: MAP1A, MetAP1A
• Location: Chr.4:98995637-99062809 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
METAP1	NM_015143.2			NP_055958.2
	XM_011531777.2			XP_011530079.1
	XM_011531778.1			XP_011530080.1
	XM_011531779.1			XP_011530081.1
	XM_017007914.1			XP_016863403.1
	XM_017007915.1			XP_016863404.1
	XM_017007916.1			XP_016863405.1
	XM_017007917.1			XP_016863406.1
	AK304239.1
	CR936632.1			CAI56775.1
	D42084.1
	DA178462.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv4438	Chr.4:99029503 - 99063090 on Build GRCh38	Insertion	METAP1
nsv1002927	Chr.4:99031321 - 99227533 on Build GRCh38	Gain	ADH5 PCNAP1 METAP1 LOC100507053 ADH6 ADH4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

regulation of translation
proteolysis
peptidyl-methionine modification
regulation of rhodopsin mediated signaling pathway
N-terminal protein amino acid modification
protein initiator methionine removal
platelet aggregation

Function(s)

aminopeptidase activity
metalloexopeptidase activity
metal ion binding
metalloaminopeptidase activity