Hs04851786_cn

• Gene Symbol: GRIA2
• Assay Reference Genome Location: Chr.4:157215785 on build GRCh38
• Cytoband: 4q32.1

Target Gene Details

• Entrez Gene ID: 2891
• Gene Name: glutamate ionotropic receptor AMPA type subunit 2
• Gene Aliases: GLUR2, GLURB, GluA2, GluR-K2, HBGR2
• Location: Chr.4:157205099-157370583 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIA2	XM_017008115.1			XP_016863604.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830123	Chr.4:157214177 - 157362103 on Build GRCh38	Gain	GRIA2
nsv1018387	Chr.4:157038779 - 157843038 on Build GRCh38	Gain	GLRB LOC340017 GRIA2

More Information

Additional Information:

For this assay, SNP(s) [rs74816882] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

signal transduction
chemical synaptic transmission
ion transmembrane transport
ionotropic glutamate receptor signaling pathway

Function(s)

ionotropic glutamate receptor activity
AMPA glutamate receptor activity
excitatory extracellular ligand-gated ion channel activity
extracellular-glutamate-gated ion channel activity
protein binding